International Journal of Biological Sciences

Impact factor
3.873

ISSN 1449-2288

News feeds of IJBS published articles
My Manuscript
My Account

Journal of Biomedicinenew

Theranostics

International Journal of Medical Sciences

Journal of Cancer

Oncomedicine

Journal of Genomics

Journal of Bone and Joint Infection (JBJI)

Nanotheranostics

PubMed Central Indexed in Journal Impact Factor

Int J Biol Sci 2005; 1(3):96-102. doi:10.7150/ijbs.1.96

Research Paper

Plasmodium species mixed infections in two areas of Manhiça District, Mozambique

P.X. Marques1, F. Saúte2 3, V.V. Pinto1, S. Cardoso1, J. Pinto1, P.L. Alonso2 4, V.E. do Rosário1, A.P. Arez1

1 Centro de Malária e outras Doenças Tropicais (CMDT), IHMT/UNL, Rua da Junqueira 96, 1349-008 Lisbon, Portugal.
2 Centro de Investigação em Saúde da Manhiça (CISM)/Ministério de Saúde, Maputo, Mozambique.
3 Instituto Nacional de Saúde, Ministério de Saúde, Maputo, Mozambique.
4 Unidad de Epidemiología y Bioestadística, Hospital Clínic, Barcelona, Spain.

Abstract

We compared the distribution patterns of individual Plasmodium species and mixed-species infections in two geographically close endemic areas, but showing environmental differences. Comparisons concerned circulating Plasmodium infections in both human and mosquito vector populations in the dry and wet seasons, at a micro-epidemiological level (households). Both areas revealed a very high overall prevalence of infection, all year-round and in all age groups. Plasmodium falciparum was the predominant species, being found in the vast majority of infected individuals regardless of the presence of other species. Plasmodium malariae and Plasmodium ovale occurred almost exclusively in mixed infections. Seasonal variation in P. malariae prevalence was observed in one area but not in the other. A decrease in P. malariae prevalence concurred with a marked increase of P. falciparum prevalence. However this was strongly dependent on age and when analysing infections at the individual level, a different pattern between co-infecting species was unveiled. Regarding transmission patterns, in both areas, P. falciparum gametocytes predominated in single infections regardless of age and P. malariae gametocyte carriage increased when its overall prevalence decreased.

Keywords: Plasmodium, mixed infections, transmission, Mozambique

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See http://ivyspring.com/terms for full terms and conditions.
How to cite this article:
Marques PX, Saúte F, Pinto VV, Cardoso S, Pinto J, Alonso PL, do Rosário VE, Arez AP. Plasmodium species mixed infections in two areas of Manhiça District, Mozambique. Int J Biol Sci 2005; 1(3):96-102. doi:10.7150/ijbs.1.96. Available from http://www.ijbs.com/v01p0096.htm