Int J Biol Sci
2019; 15(1):1-11.
doi:10.7150/ijbs.27796 This issueCite
Review
Current Progresses of Exosomes as Cancer Diagnostic and Prognostic Biomarkers
Tao Huang, Chu-Xia Deng✉
Faculty of Health Sciences, University of Macau, Macau SAR, China
✉ Corresponding author: cxdengmo
Citation:
Huang T, Deng CX. Current Progresses of Exosomes as Cancer Diagnostic and Prognostic Biomarkers. Int J Biol Sci 2019; 15(1):1-11. doi:10.7150/ijbs.27796. https://www.ijbs.com/v15p0001.htm
Cancer related exosomes are nano-size membrane vesicles that play important roles in tumor microenvironment. Emerging evidence indicates that exosomes can load unique cargoes, including proteins and nucleic acids that reflect the condition of tumor. Therefore, exosomes are being used as diagnostic and prognostic biomarkers for various cancers. In this review, we describe the current progresses of cancer related exosomes, including their biogenesis, molecular contents, biological functions, sources where they are derived from, and methods for their detection. We will also discuss the current exosomal biomarkers and the utilization of them for early diagnosis and prognostics in cancer.
Huang, T., Deng, C.X. (2019). Current Progresses of Exosomes as Cancer Diagnostic and Prognostic Biomarkers. International Journal of Biological Sciences, 15(1), 1-11. https://doi.org/10.7150/ijbs.27796.
ACS
Huang, T.; Deng, C.X. Current Progresses of Exosomes as Cancer Diagnostic and Prognostic Biomarkers. Int. J. Biol. Sci. 2019, 15 (1), 1-11. DOI: 10.7150/ijbs.27796.
NLM
Huang T, Deng CX. Current Progresses of Exosomes as Cancer Diagnostic and Prognostic Biomarkers. Int J Biol Sci 2019; 15(1):1-11. doi:10.7150/ijbs.27796. https://www.ijbs.com/v15p0001.htm
CSE
Huang T, Deng CX. 2019. Current Progresses of Exosomes as Cancer Diagnostic and Prognostic Biomarkers. Int J Biol Sci. 15(1):1-11.
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