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Int J Biol Sci 2007; 3(1):8-11. doi:10.7150/ijbs.3.8

Short Research Communication

Gamma Protocadherin Expression in the Embryonic Chick Nervous System

Kenneth D. Cronin, Anthony A. Capehart

Department of Biology, East Carolina University, Greenville, North Carolina 27858, USA


Protocadherin γ (pcdh-γ) family expression was examined in the embryonic chick central nervous system by in situ hybridization. Transcripts were visualized in discrete regions of fore-, mid-, and hindbrain at stages 23 and 25 and in spinal cord and optic lobe at stages 27 and 43, respectively. Results suggest that pcdh-γ may function cooperatively with other cell adhesion molecules in neuronal differentiation and establishment of neural networks in several areas of the developing brain, particularly regions involved in visual processing.

Keywords: cadherin, cell adhesion, central nervous system, chick embryo, neural development, protocadherin

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How to cite this article:
Cronin KD, Capehart AA. Gamma Protocadherin Expression in the Embryonic Chick Nervous System. Int J Biol Sci 2007; 3(1):8-11. doi:10.7150/ijbs.3.8. Available from