International Journal of Biological Sciences
Impact Factor

ISSN 1449-2288

News feeds of IJBS published articles

Manuscript Status/Login
Contact

Journal of Biomedicinenew

Theranostics

International Journal of Medical Sciences

Journal of Cancer

Oncomedicine

Journal of Genomics

Journal of Bone and Joint Infection (JBJI)

Nanotheranostics

PubMed Central Indexed in Journal Impact Factor
Cover image
Editor-in-Chief: Chuxia Deng, PhD, Dean and Chair Professor, Faculty of Health Sciences, University of Macau, Macau SAR, China

Editor-in-Chief's Profile

new Latest impact factor is 3.982. 5 year IF is 4.454.
new Cover suggestion ...details
Cover image
Most Cited Paper Award: Winners of this year are Zhi-Yuan Xu et al, for the paper "Knockdown of Long Non-coding RNA HOTAIR Suppresses Tumor Invasion and Reverses Epithelial-mesenchymal Transition in Gastric Cancer". Details...
The new Faculty of Health Sciences in University of Macau is recruiting Chair and Distinguished Professors, Full and Associate Professors, and Assistant Professors. ...full details
Top cited papers:
Special issue “Androgens and androgen receptor (AR) in prostate cancer” provides an update on different biological and clinical aspects of adrenal androgens, androgen biosynthetic pathways, AR-signaling, inter-racial differences in AR mutations, and clinical success and failure of antiandrogens and anti-AR therapies in prostate cancer. Androgen receptor, a nuclear steroid receptor and transcription factor, has a central role in the normal growth and development of the prostate gland, in prostate carcinogenesis, and in the castrate-resistant (CR) progression of PCa. Understanding the critical molecular events that lead PCa cells to resist antiandrogens or anti-AR therapies is essential in developing successful treatments for CR or advanced stages of the disease. ...
The synthetic cannabinoid WIN 55,212-2 is a potent cannabinoid receptor agonist with anticancer potential. Experiments were performed to determine the effects of WIN on proliferation, cell cycle distribution, and programmed cell death in human osteosarcoma MG63 and Saos-2 cells. Results show that WIN induced G2/M cell cycle arrest, which was associated with the induction of the main markers of ER stress (GRP78, CHOP and TRB3). ....details
Biochemical and biophysical processes that take place in muscle under relaxed and stressed conditions depend on the abundance and activity of gene products of metabolic and structural pathways. In livestock at post-mortem, these muscle properties determine aspects of meat quality and are measurable. The conversion of muscle to meat mimics pathological processes associated with muscle ischemia, injury or damage in humans ...details
Vγ9Vδ2 (also termed Vγ2Vδ2) T cells, a major human peripheral blood γδ T cell subset, recognize microbial (E)-4-hydroxy-3-methylbut-2-enyl diphosphate and endogenous isopentenyl diphosphate in a TCR-dependent manner. The recognition does not require specific accessory cells, antigen uptake, antigen processing, or MHC class I, class II, or class Ib expression. This subset of T cells plays important roles in mediating innate immunity against a wide variety of infections and displays potent and broad cytotoxic activity against human tumor cells. ... ...details
The behaviour of the desert locust, Schistocera gregaria, is largely directed by volatile olfactory cues. The relevant odorants are detected by specialized antennal sensory neurons which project their sensory dendrites into hair-like structures, the sensilla. Generally, the responsiveness of the antennal chemosensory cells is determined by specific receptors which may be either odorant receptors (ORs) or variant ionotropic receptors (IRs). Previously, we demonstrated that in locust the co-receptor for ORs (ORco) is only expressed in cells of sensilla basiconica and sensilla trichodea, suggesting that cells in sensilla coeloconica may express different types of chemosensory receptors. ...details
toc.jpg

Review
Cytoskeleton Molecular Motors: Structures and Their Functions in Neuron
Qingpin Xiao, Xiaohui Hu, Zhiyi Wei, Kin Yip Tam
Int. J. Biol. Sci. 2016; 12(9): 1083-1092. doi:10.7150/ijbs.15633
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Analysis of PBase Binding Profile Indicates an Insertion Target Selection Mechanism Dependent on TTAA, But Not Transcriptional Activity
Dong Yang, Ruiqi Liao, Yun Zheng, Ling Sun, Tian Xu
Int. J. Biol. Sci. 2016; 12(9): 1074-1082. doi:10.7150/ijbs.15589
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Gamma-secretase Inhibitor Prevents Proliferation and Migration of Ductus Arteriosus Smooth Muscle Cells through the Notch3-HES1/2/5 Pathway
Jiunn-Ren Wu, Jwu-Lai Yeh, Shu-Fen Liou, Zen-Kong Dai, Bin-Nan Wu, Jong-Hau Hsu
Int. J. Biol. Sci. 2016; 12(9): 1063-1073. doi:10.7150/ijbs.16430
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Alcohol Increases Liver Progenitor Populations and Induces Disease Phenotypes in Human IPSC-Derived Mature Stage Hepatic Cells
Lipeng Tian, Abhijeet Deshmukh, Neha Prasad, Yoon-Young Jang
Int. J. Biol. Sci. 2016; 12(9): 1052-1062. doi:10.7150/ijbs.15811
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Multiple Growth Factors, But Not VEGF, Stimulate Glycosaminoglycan Hyperelongation in Retinal Choroidal Endothelial Cells
Othman Al Gwairi, Narin Osman, Robel Getachew, Wenhua Zheng, X-L. Liang, Danielle Kamato, Lyna Thach, Peter J. Little
Int. J. Biol. Sci. 2016; 12(8): 1041-1051. doi:10.7150/ijbs.16134
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Rapamycin Reduced Ischemic Brain Damage in Diabetic Animals Is Associated with Suppressions of mTOR and ERK1/2 Signaling
Ping Liu, Xiao Yang, Changchun Hei, Yvonne Meli, Jianguo Niu, Tao Sun, P. Andy Li
Int. J. Biol. Sci. 2016; 12(8): 1032-1040. doi:10.7150/ijbs.15624
[Abstract] [Full text] [PDF]


toc.jpg

Review
A Review of Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer
Yi Li, Ji Wang, Xiaowei Ma, Li Tan, Yanli Yan, Chaofan Xue, Beina Hui, Rui Liu, Hailin Ma, Juan Ren
Int. J. Biol. Sci. 2016; 12(8): 1022-1031. doi:10.7150/ijbs.15438
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Cis-Natural Antisense Transcripts Are Mainly Co-expressed with Their Sense Transcripts and Primarily Related to Energy Metabolic Pathways during Muscle Development
Yunxia Zhao, Ye Hou, Changzhi Zhao, Fei Liu, Yu Luan, Lu Jing, Xinyun Li, Mengjin Zhu, Shuhong Zhao
Int. J. Biol. Sci. 2016; 12(8): 1010-1021. doi:10.7150/ijbs.14825
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Carbon Monoxide Improves Neurologic Outcomes by Mitochondrial Biogenesis after Global Cerebral Ischemia Induced by Cardiac Arrest in Rats
Peng Wang, Lan Yao, Li-li Zhou, Yuan-shan Liu, Ming-di Chen, Hai-dong Wu, Rui-ming Chang, Yi Li, Ming-gen Zhou, Xiang-shao Fang, Tao Yu, Long-yuan Jiang, Zi-tong Huang
Int. J. Biol. Sci. 2016; 12(8): 1000-1009. doi:10.7150/ijbs.13222
[Abstract] [Full text] [PDF]


Research Paper
Fibroblast Growth Factor Receptor 3 Deficiency Does Not Impair the Osteoanabolic Action of Parathyroid Hormone on Mice
Yangli Xie, Lingxian Yi, Tujun Weng, Junlan Huang, Fengtao Luo, Wanling Jiang, Cory J Xian, Xiaolan Du, Lin Chen
Int. J. Biol. Sci. 2016; 12(8): 990-999. doi:10.7150/ijbs.14077
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
BDNF-mediates Down-regulation of MicroRNA-195 Inhibits Ischemic Cardiac Apoptosis in Rats
Pengzhou Hang, Chuan Sun, Jing Guo, Jing Zhao, Zhimin Du
Int. J. Biol. Sci. 2016; 12(8): 979-989. doi:10.7150/ijbs.15071
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Selecting Cells for Bioartificial Liver Devices and the Importance of a 3D Culture Environment: A Functional Comparison between the HepaRG and C3A Cell Lines
Martien van Wenum, Aziza A.A. Adam, Theodorus B.M. Hakvoort, Erik J. Hendriks, Valery Shevchenko, Thomas M. van Gulik, Robert A.F.M. Chamuleau, Ruurdtje Hoekstra
Int. J. Biol. Sci. 2016; 12(8): 964-978. doi:10.7150/ijbs.15165
[Abstract] [Full text] [PDF]


toc.jpg

Review
The Involving Roles of Intrahepatic and Extrahepatic Stem/Progenitor Cells (SPCs) to Liver Regeneration
Wei-hui Liu, Li-na Ren, Tao Wang, Nalu Navarro-Alvarez, Li-jun Tang
Int. J. Biol. Sci. 2016; 12(8): 954-963. doi:10.7150/ijbs.15715
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Protective Effect of Thymoquinone against Cyclophosphamide-Induced Hemorrhagic Cystitis through Inhibiting DNA Damage and Upregulation of Nrf2 Expression
Prashant R. Gore, Chaitali P. Prajapati, Umesh B. Mahajan, Sameer N. Goyal, Sateesh Belemkar, Shreesh Ojha, Chandragouda R. Patil
Int. J. Biol. Sci. 2016; 12(8): 944-953. doi:10.7150/ijbs.15781
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
The Protein Elicitor PevD1 Enhances Resistance to Pathogens and Promotes Growth in Arabidopsis
Mengjie Liu, Najeeb Ullah Khan, Ningbo Wang, Xiufen Yang, Dewen Qiu
Int. J. Biol. Sci. 2016; 12(8): 931-943. doi:10.7150/ijbs.15447
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Yorkie Facilitates Organ Growth and Metamorphosis in Bombyx
Shumin Liu, Panli Zhang, Hong-Sheng Song, Hai-Sheng Qi, Zhao-Jun Wei, Guozheng Zhang, Shuai Zhan, Zhihong Liu, Sheng Li
Int. J. Biol. Sci. 2016; 12(8): 917-930. doi:10.7150/ijbs.14872
[Abstract] [Full text] [PDF]

More ...