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ISSN 1449-2288 |
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International Journal of Medical Sciences Journal of Bone and Joint Infection (JBJI) ![]() ![]() |
Int J Biol Sci 2019; 15(4):726-737. doi:10.7150/ijbs.30369 Review Autophagy in Ovarian Follicular Development and Atresia 1. Institute of Animal Science and Veterinary Medicine, Hubei Academy of Agricultural Sciences, Wuhan 430064, China Autophagy is a mechanism that exists in all eukaryotes under a variety of physiological and pathological conditions. In the mammalian ovaries, less than 1% of follicles ovulate, whereas the remaining 99% undergo follicular atresia. Autophagy and apoptosis have been previously found to be involved in the regulation of both primordial follicular development as well as atresia. The relationship between autophagy, follicular development, and atresia have been summarized in this review with the aim to obtain a more comprehensive understanding of the role played by autophagy in follicular development and atresia. Keywords: autophagy, follicular development, atresia, granulosa cells This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
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to cite this article:
Zhou J, Peng X, Mei S. Autophagy in Ovarian Follicular Development and Atresia. Int J Biol Sci 2019; 15(4):726-737. doi:10.7150/ijbs.30369. Available from http://www.ijbs.com/v15p0726.htm |