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Int J Biol Sci 2014; 10(1):109-118. doi:10.7150/ijbs.8198


Preliminary Success in the Characterization and Management of a Sudden Breakout of a Novel H7N9 Influenza A Virus

Yan-Ling Wu1✉, Li-Wen Shen2, Yan-Ping Ding1,2, Yoshimasa Tanaka3, Wen Zhang2✉

1. Lab of Molecular Immunology, Virus Inspection Department, Zhejiang Provincial Center for Disease Control and Prevention, 630 Xincheng Road, Hangzhou, 310051, PR China.
2. Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou, 310014, PR China.
3. Center for Innovation in Immunoregulative Technology and Therapeutics, Graduate School of Medicine, Kyoto University, Kyoto, 606-8501, Japan.


Influenza has always been one of the major threats to human health. The Spanish influenza in 1918, the pandemic influenza A/H1N1 in 2009, and the avian influenza A/H5N1 have brought about great disasters or losses to mankind. More recently, a novel avian influenza A/H7N9 broke out in China and until December 2, 2013, it had caused 139 cases of infection, including 45 deaths. Its risk and pandemic potential attract worldwide attention. In this article, we summarize epidemiology, virology characteristics, clinical symptoms, diagnosis methods, clinical treatment and preventive measures about the avian influenza A/H7N9 virus infection to provide a reference for a possible next wave of flu outbreak.

Keywords: H7N9 virus, avian influenza A, infection, diagnosis, treatment, prevention.

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See for full terms and conditions.
How to cite this article:
Wu YL, Shen LW, Ding YP, Tanaka Y, Zhang W. Preliminary Success in the Characterization and Management of a Sudden Breakout of a Novel H7N9 Influenza A Virus. Int J Biol Sci 2014; 10(1):109-118. doi:10.7150/ijbs.8198. Available from