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Volume 17 (6); 2021

Editorials

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The continued global battle against SARS-CoV-2 and COVID-19
Chu-Xia Deng
Int. J. Biol. Sci. 2021; 17(6): 1440-1442. doi:10.7150/ijbs.60639
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Should people with severe mental illness be prioritized for the COVID-19 vaccination?
Yuan Yang, Wen Li, Qinge Zhang, Ling Zhang, Teris Cheung, Chee H Ng, Yu-Tao Xiang
Int. J. Biol. Sci. 2021; 17(6): 1443-1445. doi:10.7150/ijbs.57750
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Papers

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Attitudes toward COVID-19 vaccines in Chinese college students
Wei Bai, Hong Cai, Shou Liu, Huanzhong Liu, Han Qi, Xu Chen, Rui Liu, Teris Cheung, Zhaohui Su, Chee H. Ng, Yu-Tao Xiang
Int. J. Biol. Sci. 2021; 17(6): 1469-1475. doi:10.7150/ijbs.58835
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Developing effective siRNAs to reduce the expression of key viral genes of COVID-19
Renfei Wu, Kathy Qian Luo
Int. J. Biol. Sci. 2021; 17(6): 1521-1529. doi:10.7150/ijbs.59151
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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SARS-CoV-2 main protease suppresses type I interferon production by preventing nuclear translocation of phosphorylated IRF3
Sin-Yee Fung, Kam-Leung Siu, Huayue Lin, Man Lung Yeung, Dong-Yan Jin
Int. J. Biol. Sci. 2021; 17(6): 1547-1554. doi:10.7150/ijbs.59943
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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In silico structure-based discovery of a SARS-CoV-2 main protease inhibitor
Lei Wen, Kaiming Tang, Kenn Ka-Heng Chik, Chris Chun-Yiu Chan, Jessica Oi-Ling Tsang, Ronghui Liang, Jianli Cao, Yaoqiang Huang, Cuiting Luo, Jian-Piao Cai, Zi-Wei Ye, Feifei Yin, Hin Chu, Dong-Yan Jin, Kwok-Yung Yuen, Shuofeng Yuan, Jasper Fuk-Woo Chan
Int. J. Biol. Sci. 2021; 17(6): 1555-1564. doi:10.7150/ijbs.59191
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Krebs Von den Lungen-6 as a predictive indicator for the risk of secondary pulmonary fibrosis and its reversibility in COVID-19 patients
Mingshan Xue, Teng Zhang, Hao Chen, Yifeng Zeng, Runpei Lin, Yingjie Zhen, Ning Li, Zhifeng Huang, Haisheng Hu, Luqian Zhou, Hui Wang, Xiaohua Douglas Zhang, Baoqing Sun
Int. J. Biol. Sci. 2021; 17(6): 1565-1573. doi:10.7150/ijbs.58825
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Reviews

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mRNA vaccines for COVID-19: what, why and how
Jung Woo Park, Philip N.P. Lagniton, Yu Liu, Ren-He Xu
Int. J. Biol. Sci. 2021; 17(6): 1446-1460. doi:10.7150/ijbs.59233
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Review of Covid-19 vaccine clinical trials - A puzzle with missing pieces
Hang Fai Kwok
Int. J. Biol. Sci. 2021; 17(6): 1461-1468. doi:10.7150/ijbs.59170
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The Genetic Variant of SARS-CoV-2: Would it matter for Controlling the Devastating Pandemic?
Shuxin Guo, Kefang Liu, Jun Zheng
Int. J. Biol. Sci. 2021; 17(6): 1476-1485. doi:10.7150/ijbs.59137
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Development and application of therapeutic antibodies against COVID-19
Lin Ning, Hamza B. Abagna, Qianhu Jiang, Siqi Liu, Jian Huang
Int. J. Biol. Sci. 2021; 17(6): 1486-1496. doi:10.7150/ijbs.59149
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Inflammatory stress in SARS-COV-2 associated Acute Kidney Injury
Junzhe Chen, Wenbiao Wang, Ying Tang, Xiao-ru Huang, Xueqing Yu, Hui-Yao Lan
Int. J. Biol. Sci. 2021; 17(6): 1497-1506. doi:10.7150/ijbs.58791
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The role of CD4+FoxP3+ regulatory T cells in the immunopathogenesis of COVID-19: implications for treatment
Yifei Wang, Jingbin Zheng, Md Sahidul Islam, Yang Yang, Yuanjia Hu, Xin Chen
Int. J. Biol. Sci. 2021; 17(6): 1507-1520. doi:10.7150/ijbs.59534
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Glucocorticoids are double-edged sword in the treatment of COVID-19 and cancers
Ruixin Yang, Yingyan Yu
Int. J. Biol. Sci. 2021; 17(6): 1530-1537. doi:10.7150/ijbs.58695
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Hydroxychloroquine/Chloroquine as Therapeutics for COVID-19: Truth under the Mystery
Yao Chen, Mei-Xiu Li, Guo-Dong Lu, Han-Ming Shen, Jing Zhou
Int. J. Biol. Sci. 2021; 17(6): 1538-1546. doi:10.7150/ijbs.59547
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Construction and applications of SARS-CoV-2 pseudoviruses: a mini review
Minghai Chen, Xian-En Zhang
Int. J. Biol. Sci. 2021; 17(6): 1574-1580. doi:10.7150/ijbs.59184
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Artificial intelligence in the diagnosis of COVID-19: challenges and perspectives
Shigao Huang, Jie Yang, Simon Fong, Qi Zhao
Int. J. Biol. Sci. 2021; 17(6): 1581-1587. doi:10.7150/ijbs.58855
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Global landscape of patents related to human coronaviruses
Kunmeng Liu, Zixuan Gu, Md Sahidul Islam, Thomas Scherngell, Xiangjun Kong, Jing Zhao, Xin Chen, Yuanjia Hu
Int. J. Biol. Sci. 2021; 17(6): 1588-1599. doi:10.7150/ijbs.58807
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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From impossible to possible: the lessons from the control of recent COVID-19 outbreaks in China
Lixin Tai, Kengieng Wong, Li Wang, Li-jun Di
Int. J. Biol. Sci. 2021; 17(6): 1600-1612. doi:10.7150/ijbs.58906
[Abstract] [Full text] [PDF] [PubMed] [PMC]