International Journal of Biological Sciences

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Volume 15 (6); 2019

Research Papers

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Hypoxia-Mimicking Cobalt-Doped Borosilicate Bioactive Glass Scaffolds with Enhanced Angiogenic and Osteogenic Capacity for Bone Regeneration
Zhengwei Deng, Bocai Lin, Zenghui Jiang, Wenhai Huang, Jiusheng Li, Xiangqiong Zeng, Hui Wang, Deping Wang, Yadong Zhang
Int. J. Biol. Sci. 2019; 15(6): 1113-1124. doi:10.7150/ijbs.32358
[Abstract] [Full text] [PDF]


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Synthetic-Evolution Reveals Narrow Paths to Regulation of the Saccharomyces cerevisiae Mitotic Kinesin-5 Cin8
Alina Goldstein, Darya Goldman, Ervin Valk, Mart Loog, Liam J. Holt, Larisa Gheber
Int. J. Biol. Sci. 2019; 15(6): 1125-1138. doi:10.7150/ijbs.30543
[Abstract] [Full text] [PDF]


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HJURP Promotes Epithelial-to-Mesenchymal Transition via Upregulating SPHK1 in Hepatocellular Carcinoma
Tianchi Chen, Lingfeng Zhou, Yuan Zhou, Wuhua Zhou, Hechen Huang, Shengyong Yin, Haiyang Xie, Lin Zhou, Shusen Zheng
Int. J. Biol. Sci. 2019; 15(6): 1139-1147. doi:10.7150/ijbs.30904
[Abstract] [Full text] [PDF]


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Causal Cortical Network for Arithmetic Problem-Solving Represents Brain's Planning Rather than Reasoning
Zhishan Hu, Keng-Fong Lam, Yu-Tao Xiang, Zhen Yuan
Int. J. Biol. Sci. 2019; 15(6): 1148-1160. doi:10.7150/ijbs.33400
[Abstract] [Full text] [PDF]


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Hypoxia preconditioned renal tubular epithelial cell-derived extracellular vesicles alleviate renal ischaemia-reperfusion injury mediated by the HIF-1α/Rab22 pathway and potentially affected by microRNAs
Lei Zhang, Han Liu, Kai Xu, Zhixin Ling, Yeqing Huang, Qiang Hu, Kai Lu, Chunhui Liu, Yiduo Wang, Ning Liu, Xiaowen Zhang, Bin Xu, Jianping Wu, Shuqiu Chen, Guangyuan Zhang, Ming Chen
Int. J. Biol. Sci. 2019; 15(6): 1161-1176. doi:10.7150/ijbs.32004
[Abstract] [Full text] [PDF]


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PCBP1 inhibits the expression of oncogenic STAT3 isoform by targeting alternative splicing of STAT3 exon 23
Xiaole Wang, Jihua Guo, Xiaoxuan Che, Rong Jia
Int. J. Biol. Sci. 2019; 15(6): 1177-1186. doi:10.7150/ijbs.33103
[Abstract] [Full text] [PDF]


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The Nuclear Export and Ubiquitin-Proteasome-Dependent Degradation of PPARγ Induced By Angiotensin II
Li Sun, Ka Bian
Int. J. Biol. Sci. 2019; 15(6): 1215-1224. doi:10.7150/ijbs.29741
[Abstract] [Full text] [PDF]


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Aplnra/b Sequentially Regulate Organ Left-Right Patterning via Distinct Mechanisms
Chengke Zhu, Zhenghua Guo, Yu Zhang, Min Liu, Bingyu Chen, Kang Cao, Yongmei Wu, Min Yang, Wenqing Yin, Haixia Zhao, Haoran Tai, Yu Ou, Xiaoping Yu, Chi Liu, Shurong Li, Bingyin Su, Yi Feng, Sizhou Huang
Int. J. Biol. Sci. 2019; 15(6): 1225-1239. doi:10.7150/ijbs.30100
[Abstract] [Full text] [PDF]


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Epigenetic Down-Regulation of Sirt 1 via DNA Methylation and Oxidative Stress Signaling Contributes to the Gestational Diabetes Mellitus-Induced Fetal Programming of Heart Ischemia-Sensitive Phenotype in Late Life
Zewen Chen, Lei Gong, Peng Zhang, Yong Li, Bailin Liu, Lubo Zhang, Jian Zhuang, Daliao Xiao
Int. J. Biol. Sci. 2019; 15(6): 1240-1251. doi:10.7150/ijbs.33044
[Abstract] [Full text] [PDF]


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Nuclear CD44 Mediated by Importin β Participated in Naïve Genes Transcriptional Regulation in C3A-iCSCs
Ming Su, Peipei Wang, Xuan Wang, Mingzhi Zhang, Shiruo Wei, Kaiyu Liu, Shuo Han, Xu Han, Yue Deng, Li Shen
Int. J. Biol. Sci. 2019; 15(6): 1252-1260. doi:10.7150/ijbs.28235
[Abstract] [Full text] [PDF]


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A CRISPR Interference of CBP and p300 Selectively Induced Synthetic Lethality in Bladder Cancer Cells In Vitro
Jianfa Li, ChenChen Huang, Tiefu Xiong, Changshui Zhuang, Chengle Zhuang, Yawen Li, Jing Ye, Yaoting Gui
Int. J. Biol. Sci. 2019; 15(6): 1276-1286. doi:10.7150/ijbs.32332
[Abstract] [Full text] [PDF]


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Novel Role of Heterogeneous Nuclear Ribonucleoprotein E1 in Regulation of Apoptosis and Autophagy by a Triazole Derivative in Vascular Endothelial Cells
Ning Meng, Yan Gong, Xin Mu, Yan Hong Wang, Le Su, Cheng Shi Jiang, Hua Zhang
Int. J. Biol. Sci. 2019; 15(6): 1299-1309. doi:10.7150/ijbs.32677
[Abstract] [Full text] [PDF]


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CSN6 Promotes the Migration and Invasion of Cervical Cancer Cells by Inhibiting Autophagic Degradation of Cathepsin L
Zun Mao, Miao-Miao Sang, Cheng Chen, Wen-Tao Zhu, Yu-Sen Gong, Dong‑Sheng Pei
Int. J. Biol. Sci. 2019; 15(6): 1310-1324. doi:10.7150/ijbs.32987
[Abstract] [Full text] [PDF]


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Combined Features Based on Preoperative Controlling Nutritional Status Score and Circulating Tumour Cell Status Predict Prognosis for Colorectal Cancer Patients Treated with Curative Resection
Chaogang Yang, Chen Wei, Shuyi Wang, Song Han, Dongdong Shi, Chunxiao Zhang, Xiaobin Lin, Rongzhang Dou, Bin Xiong
Int. J. Biol. Sci. 2019; 15(6): 1325-1335. doi:10.7150/ijbs.33671
[Abstract] [Full text] [PDF]

Reviews

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Metabolic Intermediates in Tumorigenesis and Progression
Yuchen He, Menghui Gao, Haosheng Tang, Yiqu Cao, Shuang Liu, Yongguang Tao
Int. J. Biol. Sci. 2019; 15(6): 1187-1199. doi:10.7150/ijbs.33496
[Abstract] [Full text] [PDF]


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Potential Mechanisms of Action of Curcumin for Cancer Prevention: Focus on Cellular Signaling Pathways and miRNAs
Man Wang, Shuai Jiang, Li Zhou, Fei Yu, Han Ding, Peifeng Li, Meng Zhou, Kun Wang
Int. J. Biol. Sci. 2019; 15(6): 1200-1214. doi:10.7150/ijbs.33710
[Abstract] [Full text] [PDF]


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Recent Advances in Studies of Molecular Hydrogen against Sepsis
Peng Qiu, Yang Liu, Jin Zhang
Int. J. Biol. Sci. 2019; 15(6): 1261-1275. doi:10.7150/ijbs.30741
[Abstract] [Full text] [PDF]


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Emerging Roles of p53 Related lncRNAs in Cancer Progression: A Systematic Review
Tian Lin, Ping-Fu Hou, Sen Meng, Fang Chen, Tao Jiang, Min-Le Li, Mei-Lin Shi, Jin-Jin Liu, Jun-Nian Zheng, Jin Bai
Int. J. Biol. Sci. 2019; 15(6): 1287-1298. doi:10.7150/ijbs.33218
[Abstract] [Full text] [PDF]