ISSN: 1449-2288International Journal of Biological Sciences
Global reach, higher impact
Int J Biol Sci 2010; 6(7):716-718. doi:10.7150/ijbs.6.716 This issue Cite
Commentary
Role of clusters in insulin-regulated GLUT4 trafficking in adipose cells: A new paradigm?
1. EDMNS, Diabetes Branch, NIDDK, National Institutes of Health, Bethesda, MD, USA.
2. Department of Physiology, University of South Alabama College of Medicine, Mobile, AL, USA.
Citation:
Yang J. Role of clusters in insulin-regulated GLUT4 trafficking in adipose cells: A new paradigm?. Int J Biol Sci 2010; 6(7):716-718. doi:10.7150/ijbs.6.716. https://www.ijbs.com/v06p0716.htm
Other stylesAbstract
Insulin stimulates glucose transport in muscle and adipose cells by stimulating translocation of glucose transporter 4 (GLUT4) to the plasma membrane. In a recent Cell Metabolism paper, Stenkula et al. found that insulin controls the spatial distribution of GLUT4 on the surface of isolated adipose cells through regulation of their post-fusion dispersal. The presence of GLUT4 in plasma membrane-associated clusters is suggestive of a new paradigm in membrane protein recycling.
Keywords: Adipocyte, GLUT4, exocytosis, endocytosis, insulin resistance
Citation styles
APA
Yang, J. (2010). Role of clusters in insulin-regulated GLUT4 trafficking in adipose cells: A new paradigm?. International Journal of Biological Sciences, 6(7), 716-718. https://doi.org/10.7150/ijbs.6.716.
ACS
Yang, J. Role of clusters in insulin-regulated GLUT4 trafficking in adipose cells: A new paradigm?. Int. J. Biol. Sci. 2010, 6 (7), 716-718. DOI: 10.7150/ijbs.6.716.
NLM
Yang J. Role of clusters in insulin-regulated GLUT4 trafficking in adipose cells: A new paradigm?. Int J Biol Sci 2010; 6(7):716-718. doi:10.7150/ijbs.6.716. https://www.ijbs.com/v06p0716.htm
CSE
Yang J. 2010. Role of clusters in insulin-regulated GLUT4 trafficking in adipose cells: A new paradigm?. Int J Biol Sci. 6(7):716-718.
This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See http://ivyspring.com/terms for full terms and conditions.