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Research Paper
ADAM9 functions as a transcriptional regulator to drive angiogenesis in esophageal squamous cell carcinoma
Yu-Sen Lin, Ting-Ting Kuo, Chia-Chien Lo, Wei-Chung Cheng, Wei-Chao Chang, Guan-Chin Tseng, Shih-Ting Bai, Yu-Kai Huang, Chih-Ying Hsieh, Han-Shui Hsu, Yi-Fan Jiang, Chen-Yuan Lin, Liang-Chuan Lai, Xing-Guo Li, Yuh-Pyng Sher
Int. J. Biol. Sci. 2021; 17(14): 3898-3910. doi:10.7150/ijbs.65488
[Abstract] [Full text] [PDF]


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Research Paper
The intraviral protein-protein interaction of SARS-CoV-2 reveals the key role of N protein in virus-like particle assembly
Minghai Chen, Chuang Yan, Fujun Qin, Luping Zheng, Xian-En Zhang
Int. J. Biol. Sci. 2021; 17(14): 3889-3897. doi:10.7150/ijbs.64977
[Abstract] [Full text] [PDF]


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Research Paper
Up-regulation of MELK by E2F1 promotes the proliferation in cervical cancer cells
Hongzhi Sun, Hongmei Ma, Hao Zhang, Minjun Ji
Int. J. Biol. Sci. 2021; 17(14): 3875-3888. doi:10.7150/ijbs.62517
[Abstract] [Full text] [PDF]


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Research Paper
FGF7-induced E11 facilitates cell-cell communication through connexin43
Xiaoyu Liu, Mingru Bai, Yimin Sun, Xuchen Hu, Chenglin Wang, Jing Xie, Ling Ye
Int. J. Biol. Sci. 2021; 17(14): 3862-3874. doi:10.7150/ijbs.65240
[Abstract] [Full text] [PDF]


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Research Paper
Development of mesothelin-specific CAR NK-92 cells for the treatment of gastric cancer
Bihui Cao, Manting Liu, Jingjun Huang, Jingwen Zhou, Junping Li, Hui Lian, Wensou Huang, Yongjian Guo, Shuo Yang, Liteng Lin, Mingyue Cai, Cheng Zhi, Jingqiang Wu, Licong Liang, Yuling Hu, Hong Hu, Jinping He, Baoxia Liang, Qi Zhao, Kangshun Zhu
Int. J. Biol. Sci. 2021; 17(14): 3850-3861. doi:10.7150/ijbs.64630
[Abstract] [Full text] [PDF]


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Review
Immunotherapy in colorectal cancer: current achievements and future perspective
Ahui Fan, Boda Wang, Xin Wang, Yongzhan Nie, Daiming Fan, Xiaodi Zhao, Yuanyuan Lu
Int. J. Biol. Sci. 2021; 17(14): 3837-3849. doi:10.7150/ijbs.64077
[Abstract] [Full text] [PDF]


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Research Paper
Melittin-loaded Iron Oxide Nanoparticles Prevent Intracranial Arterial Dolichoectasia Development through Inhibition of Macrophage-mediated Inflammation
Huy Duc Vu, Phuong Tu Huynh, Junghwa Ryu, Ung Rae Kang, Sung Won Youn, Hongtae Kim, Hyun Jin Ahn, Kwankyu Park, Soon-Kyung Hwang, Young-Chae Chang, Yong Jig Lee, Hui Joong Lee, Jongmin Lee
Int. J. Biol. Sci. 2021; 17(14): 3818-3836. doi:10.7150/ijbs.60588
[Abstract] [Full text] [PDF]


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Research Paper
Comprehensive landscape of the renin-angiotensin system in Pan-cancer: a potential downstream mediated mechanism of SARS-CoV-2
Yuqing Cui, Fengzhi Chen, Jiayi Gao, Mengxia Lei, Dandan Wang, Xiaoying Jin, Yan Guo, Liying Shan, Xuesong Chen
Int. J. Biol. Sci. 2021; 17(14): 3795-3817. doi:10.7150/ijbs.53312
[Abstract] [Full text] [PDF]


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Research Paper
Receptor-binding domain of SARS-CoV-2 spike protein efficiently inhibits SARS-CoV-2 infection and attachment to mouse lung
Hye Jin Shin, Keun Bon Ku, Hae Soo Kim, Hyun Woo Moon, Gi Uk Jeong, Insu Hwang, Gun Young Yoon, Sunhee Lee, Sumin Lee, Dae-Gyun Ahn, Kyun-Do Kim, Young-Chan Kwon, Bum-Tae Kim, Seong-Jun Kim, Chonsaeng Kim
Int. J. Biol. Sci. 2021; 17(14): 3786-3794. doi:10.7150/ijbs.61320
[Abstract] [Full text] [PDF]


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Research Paper
YTHDF2 Suppresses Notch Signaling through Post-transcriptional Regulation on Notch1
Byongsun Lee, Seungjae Lee, Jaekyung Shim
Int. J. Biol. Sci. 2021; 17(14): 3776-3785. doi:10.7150/ijbs.61573
[Abstract] [Full text] [PDF]


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Research Paper
Single-cell RNA sequencing reveals spatiotemporal heterogeneity and malignant progression in pancreatic neuroendocrine tumor
Yu Zhou, Siyang Liu, Chao Liu, Jiabin Yang, Qing Lin, Shangyou Zheng, Changhao Chen, Quanbo Zhou, Rufu Chen
Int. J. Biol. Sci. 2021; 17(14): 3760-3775. doi:10.7150/ijbs.61717
[Abstract] [Full text] [PDF]


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Research Paper
Lipotoxic hepatocytes promote nonalcoholic fatty liver disease progression by delivering microRNA-9-5p and activating macrophages
Hanyun Liu, Qinghui Niu, Ting Wang, Hongjing Dong, Cheng Bian
Int. J. Biol. Sci. 2021; 17(14): 3745-3759. doi:10.7150/ijbs.57610
[Abstract] [Full text] [PDF]


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Research Paper
Melatonin and hyperbaric oxygen therapies suppress colorectal carcinogenesis through pleiotropic effects and multifaceted mechanisms
Yi-Chen Li, Chih-Hung Chen, Chia-Lo Chang, John Yi-Wu Chiang, Chi-Hsiang Chu, Hong-Hwa Chen, Hon-Kan Yip
Int. J. Biol. Sci. 2021; 17(14): 3728-3744. doi:10.7150/ijbs.62280
[Abstract] [Full text] [PDF]


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Research Paper
Gene Presence/Absence Variation analysis of coronavirus family displays its pan-genomic diversity
Du Jiao, Xiaorui Dong, Yingyan Yu, Chaochun Wei
Int. J. Biol. Sci. 2021; 17(14): 3717-3727. doi:10.7150/ijbs.58220
[Abstract] [Full text] [PDF]


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Research Paper
Suppression of neuronal cholesterol biosynthesis impairs brain functions through insulin-like growth factor I-Akt signaling
Ting Liu, Yang Li, Baoyu Yang, Haozhen Wang, Chen Lu, Alan K Chang, Xiuting Huang, Xiujin Zhang, Ziyin Lu, Xiuli Lu, Bing Gao
Int. J. Biol. Sci. 2021; 17(14): 3702-3716. doi:10.7150/ijbs.63512
[Abstract] [Full text] [PDF]


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Research Paper
Cancer-associated fibroblasts-derived exosomal miR-3656 promotes the development and progression of esophageal squamous cell carcinoma via the ACAP2/PI3K-AKT signaling pathway
Yuan Jin, Qilin Meng, Bihui Zhang, Chen Xie, Xue Chen, Baoqing Tian, Jiakang Wang, Tsung-Chieh Shih, Yibo Zhang, Jieqiong Cao, Yiqi Yang, Size Chen, Xinyuan Guan, Xiaojia Chen, An Hong
Int. J. Biol. Sci. 2021; 17(14): 3689-3701. doi:10.7150/ijbs.62571
[Abstract] [Full text] [PDF]

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Editor-in-Chief: Chuxia Deng, PhD, Dean and Chair Professor, Faculty of Health Sciences, University of Macau

Editor-in-Chief's Profile

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new🆘The continued global battle against SARS-CoV-2 and COVID-19: Special issue on Coronavirus disease https://www.ijbs.com/v17i6

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Postdoctoral Fellowship and Associateship available in Faculty of Health Sciences (FHS),University of Macau ...full details
Journal of Genomics articles:

Research Paper
Genetic Diversity of Clinical Bordetella Pertussis ST2 Strains in comparison with Vaccine Reference Strains of India
Naresh Chand Sharma, Shalini Anandan, Naveen Kumar Devanga Ragupathi, Dhiviya Prabaa Muthuirulandi Sethuvel, Karthick Vasudevan, Dhirendra Kumar, Sushil Kumar Gupta, Lucky Sangal, Balaji Veeraraghavan
J. Genomics 2021; 9: 38-42. doi:10.7150/jgen.58823
[Abstract] [Full text] [PDF] [PMC]


Research Paper
Analysis of Genome Sequences of Coagulase-Negative Staphylococci Isolates from South Africa and Nigeria Highlighted Environmentally Driven Heterogeneity
Tawanda Elias Maguvu, Adegboyega Oyedele Oladipo, Cornelius Carlos Bezuidenhout
J. Genomics 2021; 9: 26-37. doi:10.7150/jgen.53019
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Research Paper
Draft genome sequences of three filamentous cyanobacteria isolated from brackish habitats
Joanne Sarah Boden, Michele Grego, Henk Bolhuis, Patricia Sánchez-Baracaldo
J. Genomics 2021; 9: 20-25. doi:10.7150/jgen.53678
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Review
The Genetic Background of Central Serous Chorioretinopathy: A Review on Central Serous Chorioretinopathy Genes
Konstantinos Giannopoulos, Maria Gazouli, Klio Chatzistefanou, Anthi Bakouli, Marilita M Moschos
J. Genomics 2021; 9: 10-19. doi:10.7150/jgen.55545
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Top cited papers: