Research Paper
In vivo CRISPR/Cas9 Screening Reveals that UBE2L3 Modulates Autophagic Flux through TSC2 Ubiquitination and Potentiates PD-1 Blockade in Triple-Negative Breast Cancer
Jian Xu, Ling Cheng, Sien Ma, Chen Gan, Jiaying Chai, Xinyi Zheng, Longyu Hu, Meiwen Ling, Mingjun Zhang, Bao Zhao, Huaidong Cheng
Int. J. Biol. Sci. 2026; 22(6): 2950-2969. doi:10.7150/ijbs.124937
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Research Paper
Investigating the Mechanistic Link Between Lactate-Induced Histone Lactylation and Cellular Senescence in Osteoarthritis Chondrocytes: Implications for Therapy
Rongtai Zuo, Chenliang Wu, Zhiqi Lin, Lingchi Kong, Feng Wang, Xuancheng Zhang, Jianxing Wei, Yi Lin, Erpeng Yang, Qinglin Kang, Shichang Zhao, Junjie Guan, Jinzhong Zhao
Int. J. Biol. Sci. 2026; 22(6): 2925-2949. doi:10.7150/ijbs.126483
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Review
Orchestrating Tumor Metastasis: Exosomes as Master Regulators of the Local and Distant Microenvironment
Yuanke Zhao, Aiyu Liu, Xi Zhang, Anqi Zeng, Linjiang Song
Int. J. Biol. Sci. 2026; 22(6): 2906-2924. doi:10.7150/ijbs.128203
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Research Paper
Synergistic Neurotoxicity of environmental Cadmium and Paraquat in Parkinsonism: Unveiling the Mito-ROS/OPA1/Caspase-3/GSDME-driven Apoptosis Axis
Yufei Luo, Yingying Lu, Yancheng Tang, Xuejun Zhao, Junpu Wang, Yifan Liu, Sijia Jiang, Yuyuan Zhu, Jiaqi Qi, Linlin Xing, Chenghao Yan, Xu Liu, Cainian Huang, Haiji Wang, Haodong Xu, Liming Wang
Int. J. Biol. Sci. 2026; 22(6): 2885-2905. doi:10.7150/ijbs.126979
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Research Paper
Clonotype-Resolved Single-Cell Multi-Omics Unlocks the Profile of Tumor-Infiltrating CD39⁺CD8⁺ T Cells and Enables Adoptive Cell Therapy for Solid Tumor
Zihan Zhao, Xiangyu Wu, Qingyang Jin, Xin Yang, Wenjie Zhu, Ning Jiang, Tianyao Liu, Tianhang Li, Feng Fang, Hongqian Guo, Rong Yang
Int. J. Biol. Sci. 2026; 22(6): 2869-2884. doi:10.7150/ijbs.130389
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Review
Role of Copper Homeostasis and Cuproptosis in Cardiovascular Disease: Molecular Insights and Metabolic Perspectives
Xianzhe Yu, Dou Yuan, Yabo Wang, Leibo Wang, Lingling Zhu, Qi An, Yunfei Ling
Int. J. Biol. Sci. 2026; 22(6): 2842-2868. doi:10.7150/ijbs.126580
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Issue 4; 2026
Editor-in-Chief: Chuxia Deng, PhD, Dean and Chair Professor,
Faculty of Health Sciences, University of Macau
Editor-in-Chief's Profile
Plagiarism Policy (please read before submission): This journal maintains a zero-tolerance policy towards plagiarism. Manuscripts are screened for plagiarism before and after publication. If a published paper is found to contain plagiarism, it will be retracted and the authors' institutions and department heads will be notified to take appropriate action. This policy also applies to data fabrication and image manipulation.
Research Paper
Draft Genomes of Geographically Distinct Strains and Progeny of the Ectomycorrhizal Basidiomycete Laccaria bicolor
Francis M. Martin, Emmanuelle Morin, Alan Kuo, Igor Miquel, Jessy Labbé, François Le Tacon, Laure Fauchery, Annegret Kohler, William Andreopoulos, Alex Copeland, Hui Sun, Asaf Salamov, Anna Lipzen, James Han, Kurt LaButti, Andrew Tritt, Kerry Barry, Igor V. Grigoriev
J. Genomics 2026; 14: 10-17.
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