Review
Advances in Multi-Omics Study of Prognostic Biomarkers of Diffuse Large B-Cell Lymphoma
Xiao-jie Liang, Xin-yu Song, Jia-lin Wu, Dan Liu, Bing-yu Lin, Hong-sheng Zhou, Liang Wang
Int. J. Biol. Sci. 2022; 18(4): 1313-1327. doi:10.7150/ijbs.67892
[Abstract] [Full text] [PDF]

Review
Role of Slit/Robo Signaling pathway in Bone Metabolism
Lingyu Jiang, Jianxun Sun, Dingming Huang
Int. J. Biol. Sci. 2022; 18(3): 1303-1312. doi:10.7150/ijbs.66931
[Abstract] [Full text] [PDF]

Research Paper
VRK2 activates TNFα/NF-κB signaling by phosphorylating IKKβ in pancreatic cancer
Jionghuang Chen, Kexiong Qiao, Chaolei Zhang, Xinyang Zhou, Qian Du, Yuezhen Deng, Liping Cao
Int. J. Biol. Sci. 2022; 18(3): 1288-1302. doi:10.7150/ijbs.66313
[Abstract] [Full text] [PDF]

Research Paper
CXCR4-dependent macrophage-to-fibroblast signaling contributes to cardiac diastolic dysfunction in heart failure with preserved ejection fraction
Ning Zhang, Qunchao Ma, Yayu You, Xiangyang Xia, Cuiping Xie, Yuxue Huang, Zhuo Wang, Feiming Ye, Zhaosheng Yu, Xiaojie Xie
Int. J. Biol. Sci. 2022; 18(3): 1271-1287. doi:10.7150/ijbs.65802
[Abstract] [Full text] [PDF]

Research Paper
Integrin-β4 regulates the dynamic changes of phenotypic characteristics in association with epithelial-mesenchymal transition (EMT) and RhoA activity in airway epithelial cells during injury and repair
Mei-Ling Tan, Wen-Jie Huang, Yue Wang, Lei Liu, Yan Pan, Jing-Jing Li, Jiang Zhang, Mingxing Ouyang, Xiang-Ping Qu, Hui-Jun Liu, Chi Liu, Dan Zeng, Xiao-Qun Qin, Linhong Deng, Yang Xiang
Int. J. Biol. Sci. 2022; 18(3): 1254-1270. doi:10.7150/ijbs.65174
[Abstract] [Full text] [PDF]

Research Paper
Poly (ADP-ribose) polymerase 1 (PARP1) inhibition promotes pulmonary metastasis of osteosarcoma by boosting ezrin phosphorylation
Fangfei Li, Xiaoqiu Wu, Xuekun Fu, Jin Liu, Wangze Song, Gary Guishan Xiao, Aiping Lu, Ge Zhang
Int. J. Biol. Sci. 2022; 18(3): 1238-1253. doi:10.7150/ijbs.58784
[Abstract] [Full text] [PDF]

Research Paper
Hypoxic pancreatic cancer derived exosomal miR-30b-5p promotes tumor angiogenesis by inhibiting GJA1 expression
Kai Chen, Qi Wang, Xinxin Liu, Feng Wang, Yinmo Yang, Xiaodong Tian
Int. J. Biol. Sci. 2022; 18(3): 1220-1237. doi:10.7150/ijbs.67675
[Abstract] [Full text] [PDF]

Review
DNA Replication Licensing Factors: Novel Targets for Cancer Therapy via Inhibiting the Stemness of Cancer Cells
Shaoran Song, Yaochun Wang, Peijun Liu
Int. J. Biol. Sci. 2022; 18(3): 1211-1219. doi:10.7150/ijbs.67529
[Abstract] [Full text] [PDF]

Research Paper
HJURP Promotes Malignant Progression and Mediates Sensitivity to Cisplatin and WEE1-inhibitor in Serous Ovarian Cancer
Zhiyuan Dou, Chunping Qiu, Xun Zhang, Shu Yao, Chen Zhao, Zixiang Wang, Ran Chu, Jingying Chen, Zhongshao Chen, Rongrong Li, Kun Wang, Penglin Liu, Chang Liu, Kun Song, Beihua Kong
Int. J. Biol. Sci. 2022; 18(3): 1188-1210. doi:10.7150/ijbs.65589
[Abstract] [Full text] [PDF]

Research Paper
CD137L-macrophage induce lymphatic endothelial cells autophagy to promote lymphangiogenesis in renal fibrosis
Haotian Wei, Li Chen, Qing Li, Xinjun Liang, Kun Wang, Ying Zhang, Yueqiang Li, Yanyan Liu, Gang Xu
Int. J. Biol. Sci. 2022; 18(3): 1171-1187. doi:10.7150/ijbs.66781
[Abstract] [Full text] [PDF]

Review
Insight of Autophagy in Spontaneous Miscarriage
Xue-Yun Qin, Hui-Hui Shen, Wen-Jie Zhou, Jie Mei, Han Lu, Xiao-Fang Tan, Rui Zhu, Wen-Hui Zhou, Da-Jin Li, Tao Zhang, Jiang-Feng Ye, Ming-Qing Li
Int. J. Biol. Sci. 2022; 18(3): 1150-1170. doi:10.7150/ijbs.68335
[Abstract] [Full text] [PDF]

Research Paper
TBL1X and Flot2 form a positive feedback loop to promote metastasis in nasopharyngeal carcinoma
Hongjuan Xu, Xuejun Yan, Hecheng Zhu, Yuanbo Kang, Weiren Luo, Jin Zhao, Kefan Zhou, Xiwu Liu, Li Ye, Quanwei Zhou, Shasha Li, Ming Zhao, Lei Wang, Bin Zhu, Weidong Liu, Jianxiong Li, Xingjun Jiang, Caiping Ren
Int. J. Biol. Sci. 2022; 18(3): 1134-1149. doi:10.7150/ijbs.68091
[Abstract] [Full text] [PDF]

Research Paper
High Expression of G6PD Increases Doxorubicin Resistance in Triple Negative Breast Cancer Cells by Maintaining GSH Level
Man Luo, Afu Fu, Renfei Wu, Na Wei, Kai Song, Sierin Lim, Kathy Qian Luo
Int. J. Biol. Sci. 2022; 18(3): 1120-1133. doi:10.7150/ijbs.65555
[Abstract] [Full text] [PDF]

Research Paper
The Role of Autophagy in Lamellar Body Formation and Surfactant Production in Type 2 Alveolar Epithelial Cells
Xiaoman Li, Liang Wang, Jialin Hao, Qingfeng Zhu, Min Guo, Changjing Wu, Sihui Li, Qiqiang Guo, Qiuhong Ren, Ning Bai, Fei Yi, Bo Jiang, Wenyu Zhang, Yanling Feng, Hongde Xu, Han Jiang, Xiaoyue Zhai, Guohua Zhang, Hong-long Ji, Xuesong Yang, Dan Zhang, Jianhua Fu, Jianjun Chang, Xiaoyu Song, Liu Cao
Int. J. Biol. Sci. 2022; 18(3): 1107-1119. doi:10.7150/ijbs.64285
[Abstract] [Full text] [PDF]

Research Paper
The role of MLKL in Hepatic Ischemia-Reperfusion Injury of Alcoholic Steatotic Livers
Hao Chen, Tara McKeen, Xiaojuan Chao, Allen Chen, Fengyan Deng, Hartmut Jaeschke, Wen-Xing Ding, Hong-Min Ni
Int. J. Biol. Sci. 2022; 18(3): 1096-1106. doi:10.7150/ijbs.67533
[Abstract] [Full text] [PDF]

Research Paper
Multimerization of the GATA4 transcription factor regulates transcriptional activity and cardiomyocyte hypertrophic response
Satoshi Shimizu, Yoichi Sunagawa, Naruto Hajika, Natsumi Yorimitsu, Yasufumi Katanasaka, Masafumi Funamoto, Yusuke Miyazaki, Nurmila Sari, Kana Shimizu, Koji Hasegawa, Tatsuya Morimoto
Int. J. Biol. Sci. 2022; 18(3): 1079-1095. doi:10.7150/ijbs.65664
[Abstract] [Full text] [PDF]

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