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Research Paper
The effect of HMGA1 in LPS-induced Myocardial Inflammation
Zhu-Lan Cai, Bo Shen, Yuan Yuan, Chen Liu, Qing-Wen Xie, Tong-Tong Hu, Qi Yao, Qing-Qing Wu, Qi-Zhu Tang
Int. J. Biol. Sci. 2020; 16(11): 1798-1810. doi:10.7150/ijbs.39947
[Abstract] [Full text] [PDF]


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Research Paper
Diagnostic, progressive and prognostic performance of m6A methylation RNA regulators in lung adenocarcinoma
Zhizhi Zhuang, Liping Chen, Yuting Mao, Qun Zheng, Huiying Li, Yueyue Huang, Zijing Hu, Yi Jin
Int. J. Biol. Sci. 2020; 16(11): 1785-1797. doi:10.7150/ijbs.39046
[Abstract] [Full text] [PDF]


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Research Paper
Histone Acetyltransferase (HAT) P300/CBP Inhibitors Induce Synthetic Lethality in PTEN-Deficient Colorectal Cancer Cells through Destabilizing AKT
Yifan Liu, Eun Ju Yang, Changxiang Shi, Pui Kei Mou, Baoyuan Zhang, Changjie Wu, Junfang Lyu, Joong Sup Shim
Int. J. Biol. Sci. 2020; 16(11): 1774-1784. doi:10.7150/ijbs.42197
[Abstract] [Full text] [PDF]


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Review
B7-H3, a checkpoint molecule, as a target for cancer immunotherapy
Shuo Yang, Wei Wei, Qi Zhao
Int. J. Biol. Sci. 2020; 16(11): 1767-1773. doi:10.7150/ijbs.41105
[Abstract] [Full text] [PDF]


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Review
COVID-19: what has been learned and to be learned about the novel coronavirus disease
Ye Yi, Philip N.P. Lagniton, Sen Ye, Enqin Li, Ren-He Xu
Int. J. Biol. Sci. 2020; 16(10): 1753-1766. doi:10.7150/ijbs.45134
[Abstract] [Full text] [PDF] [PMC]


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Research Paper
Knowledge, attitudes, and practices towards COVID-19 among Chinese residents during the rapid rise period of the COVID-19 outbreak: a quick online cross-sectional survey
Bao-Liang Zhong, Wei Luo, Hai-Mei Li, Qian-Qian Zhang, Xiao-Ge Liu, Wen-Tian Li, Yi Li
Int. J. Biol. Sci. 2020; 16(10): 1745-1752. doi:10.7150/ijbs.45221
[Abstract] [Full text] [PDF] [PMC]


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Review
The COVID-19 outbreak and psychiatric hospitals in China: managing challenges through mental health service reform
Yu-Tao Xiang, Yan-Jie Zhao, Zi-Han Liu, Xiao-Hong Li, Na Zhao, Teris Cheung, Chee H. Ng
Int. J. Biol. Sci. 2020; 16(10): 1741-1744. doi:10.7150/ijbs.45072
[Abstract] [Full text] [PDF] [PMC]


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Review
Tribute to health workers in China: A group of respectable population during the outbreak of the COVID-19
Yu-Tao Xiang, Yu Jin, Yu Wang, Qinge Zhang, Ling Zhang, Teris Cheung
Int. J. Biol. Sci. 2020; 16(10): 1739-1740. doi:10.7150/ijbs.45135
[Abstract] [Full text] [PDF] [PMC]


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Review
Progression of Mental Health Services during the COVID-19 Outbreak in China
Wen Li, Yuan Yang, Zi-Han Liu, Yan-Jie Zhao, Qinge Zhang, Ling Zhang, Teris Cheung, Yu-Tao Xiang
Int. J. Biol. Sci. 2020; 16(10): 1732-1738. doi:10.7150/ijbs.45120
[Abstract] [Full text] [PDF] [PMC]


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Review
Targeting the Endocytic Pathway and Autophagy Process as a Novel Therapeutic Strategy in COVID-19
Naidi Yang, Han-Ming Shen
Int. J. Biol. Sci. 2020; 16(10): 1724-1731. doi:10.7150/ijbs.45498
[Abstract] [Full text] [PDF] [PMC]


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Review
Perspectives on therapeutic neutralizing antibodies against the Novel Coronavirus SARS-CoV-2
Guangyu Zhou, Qi Zhao
Int. J. Biol. Sci. 2020; 16(10): 1718-1723. doi:10.7150/ijbs.45123
[Abstract] [Full text] [PDF] [PMC]


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Review
Traditional Chinese Medicine in the Treatment of Patients Infected with 2019-New Coronavirus (SARS-CoV-2): A Review and Perspective
Yang Yang, Md Shahidul Islam, Jin Wang, Yuan Li, Xin Chen
Int. J. Biol. Sci. 2020; 16(10): 1708-1717. doi:10.7150/ijbs.45538
[Abstract] [Full text] [PDF] [PMC]


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Research Paper
Evaluation of SARS-CoV-2 RNA shedding in clinical specimens and clinical characteristics of 10 patients with COVID-19 in Macau
Iek Long Lo, Chon Fu Lio, Hou Hon Cheong, Chin Ion Lei, Tak Hong Cheong, Xu Zhong, Yakun Tian, Nin Ngan Sin
Int. J. Biol. Sci. 2020; 16(10): 1698-1707. doi:10.7150/ijbs.45357
[Abstract] [Full text] [PDF] [PMC]


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Review
Zoonotic origins of human coronaviruses
Zi-Wei Ye, Shuofeng Yuan, Kit-San Yuen, Sin-Yee Fung, Chi-Ping Chan, Dong-Yan Jin
Int. J. Biol. Sci. 2020; 16(10): 1686-1697. doi:10.7150/ijbs.45472
[Abstract] [Full text] [PDF] [PMC]


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Review
SARS-CoV-2: an Emerging Coronavirus that Causes a Global Threat
Jun Zheng
Int. J. Biol. Sci. 2020; 16(10): 1678-1685. doi:10.7150/ijbs.45053
[Abstract] [Full text] [PDF] [PMC]


Editorial
The global battle against SARS-CoV-2 and COVID-19
Chu-Xia Deng
Int. J. Biol. Sci. 2020; 16(10): 1676-1677. doi:10.7150/ijbs.45587
[Abstract] [Full text] [PDF] [PMC]

Cover image
Editor-in-Chief: Chuxia Deng, PhD, Dean and Chair Professor, Faculty of Health Sciences, University of Macau

Editor-in-Chief's Profile

Impact factor is 4.067 according to 2019 release of Journal Citation Reports®.

🆘 The global battle against SARS-CoV-2 and COVID-19: Special issue on Coronavirus disease https://www.ijbs.com/v16i10

Postdoctoral Fellowship and Associateship available in Faculty of Health Sciences (FHS),University of Macau ...full details
Journal of Genomics articles:

Research Paper
Programmable CRISPR interference for gene silencing using Cas13a in mosquitoes
Aditi Kulkarni, Wanqin Yu, Alex Moon, Ashmita Pandey, Kathryn A. Hanley, Jiannong Xu
J. Genomics 2020; 8: 30-36. doi:10.7150/jgen.43928
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Research Paper
Draft Genome Analysis of Christensenella minuta DSM 22607, exhibiting an unusual expansion of transporter homologs of unknown function
David A Coil, Guillaume Jospin, Jonathan A. Eisen
J. Genomics 2020; 8: 25-29. doi:10.7150/jgen.43162
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Short Research Paper
Draft genome sequence of Deinococcus sp. KR-1, a potential strain for palladium-leaching
Hironaga Akita, Yuya Itoiri, Akio Kumagai, Noriyo Takeda, Akinori Matsushika, Mamoru Oshiki, Zen-ichiro Kimura
J. Genomics 2020; 8: 21-24. doi:10.7150/jgen.42020
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Research Paper
Isolation and genomic analysis of 11-aminoundecanoic acid-degrading bacterium Pseudomonas sp. JG-B from nylon 11 enrichment culture
Jocelyn Gatz-Schrupp, Peter Deckard, Benjamin Hufford, Steven Ly, Peter Tupa, Hisako Masuda
J. Genomics 2020; 8: 16-20. doi:10.7150/jgen.42095
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Top cited papers:
The amyloid precursor protein plus presenilin-1 (APP/PS1) mice are a frequently-used model for Alzheimer's disease studies (AD). However, the data relevant to which proteins are involved in inflammatory mechanism are not sufficiently well-studied using the AD mouse model. Using behavioral studies, quantitative RT-PCR and Western-blot techniques, significant findings were determined by the expression of proteins involved in inflammation comparing APP/PS1 and Wild type mice. Increased GFAP expression could be associated with the elevation in number of reactive astrocytes.. ....details
Recently, interest in IL-15-differentiated cells has increased; however, the phenotypic definition of IL-15-differentiated bone marrow-derived cells (IL-15-DBMCs) is still under debate, particularly the generation of IFN-γ-producing innate cells such as premature NK (pre-mNK) cells, natural killer dendritic cells (NKDCs), interferon-producing killer dendritic cells (IKDCs), and type 1 innate lymphoid cells (ILC1s), all of which are IL-15-dependent. Here, we revisited the immunophenotypic characteristics of IFN-γ-producing IL-15-DBMCs and their functional role in the control of intracellular Mycobacterium tuberculosis (Mtb) infection.. ....details
Bone marrow-derived progenitor cell-mediated vasculogenesis is a key process for vascular repair and regeneration. However, the role of androgens in the mechanism of ischemia-induced vasculogenesis remains unclear. In this study, a gender-mismatch murine bone marrow transplant model was used to allow tissue tracking of transplanted cells. Bone marrow from 2-month-old male mice was transplanted into irradiated age-matched female recipients. Following the transplantation, ovariectomized female recipients were subjected to unilateral hindlimb ischemia and immediately implanted with either dihydrotestosterone (DHT) or placebo pellets. Laser Doppler perfusion imaging revealed that DHT significantly augmented blood flow recovery, with increased capillary density compared to placebo-treated female recipient controls.. ....details
In this review, we describe the current progresses of cancer related exosomes, including their biogenesis, molecular contents, biological functions, sources where they are derived from, and methods for their detection. We will also discuss the current exosomal biomarkers and the utilization of them for early diagnosis and prognostics in cancer. ... ...details