Research Paper
Synergism of FAK and ROS1 inhibitors in the treatment of CDH1-deficient cancers mediated by FAK-YAP signaling
Jiaming Gao, Yunying Yao, Chenxuan Liu, Xi Xie, Donghe Li, Ping Liu, Zaiqi Wang, Baoyuan Zhang, Ruibao Ren
Int. J. Biol. Sci. 2023; 19(9): 2711-2724. doi:10.7150/ijbs.81918
[Abstract] [Full text] [PDF]

Research Paper
Stroke by inducing HDAC9-dependent deacetylation of HIF-1 and Sp1, promotes TfR1 transcription and GPX4 reduction, thus determining ferroptotic neuronal death
Luca Sanguigno, Natascia Guida, Serenella Anzilotti, Ornella Cuomo, Luigi Mascolo, Angelo Serani, Paola Brancaccio, Giuseppina Pennacchio, Ester Licastro, Giuseppe Pignataro, Pasquale Molinaro, Lucio Annunziato, Luigi Formisano
Int. J. Biol. Sci. 2023; 19(9): 2695-2710. doi:10.7150/ijbs.80735
[Abstract] [Full text] [PDF]

Review
Emerging Role of Ferroptosis in Diabetic Kidney Disease: Molecular Mechanisms and Therapeutic Opportunities
Hui Wang, Dongwei Liu, Bin Zheng, Yang Yang, Yingjin Qiao, Shiyang Li, Shaokang Pan, Yong Liu, Qi Feng, Zhangsuo Liu
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[Abstract] [Full text] [PDF]

Research Paper
Heme-binding protein 1 delivered via pericyte-derived extracellular vesicles improves neurovascular regeneration in a mouse model of cavernous nerve injury
Jiyeon Ock, Jitao Wu, Fang-Yuan Liu, Fitri Rahma Fridayana, Lashkari Niloofar, Minh Nhat Vo, Soon-Sun Hong, Ju-Hee Kang, Jun-Kyu Suh, Guo Nan Yin, Hai-Rong Jin, Ji-Kan Ryu
Int. J. Biol. Sci. 2023; 19(9): 2663-2677. doi:10.7150/ijbs.81809
[Abstract] [Full text] [PDF]

Research Paper
Induction of Immune Responses and Phosphatidylserine Exposure by TLR9 Activation Results in a Cooperative Antitumor Effect with a Phosphatidylserine-targeting Prodrug
Jen-Chih Tseng, Jing-Xing Yang, Chia-Yin Lee, Chen-Fu Lo, Yi-Ling Liu, Mingzi M. Zhang, Li-Rung Huang, Ko-Jiunn Liu, Chien-Chia Wang, Chi-Ying F. Huang, Yi-Ren Hong, Lun K. Tsou, Tsung-Hsien Chuang
Int. J. Biol. Sci. 2023; 19(9): 2648-2662. doi:10.7150/ijbs.81683
[Abstract] [Full text] [PDF]

Research Paper
Dendropanoxide Alleviates Thioacetamide-induced Hepatic Fibrosis via Inhibition of ROS Production and Inflammation in BALB/_C Mice
Amit Kundu, Sreevarsha Gali, Swati Sharma, Sam Kacew, Sungpil Yoon, Hye Gwang Jeong, Jong Hwan Kwak, Hyung Sik Kim
Int. J. Biol. Sci. 2023; 19(9): 2630-2647. doi:10.7150/ijbs.80743
[Abstract] [Full text] [PDF]

Research Paper
ACE2 negatively regulates the Warburg effect and suppresses hepatocellular carcinoma progression via reducing ROS-HIF1α activity
Fangyuan Dong, Hui Li, Limin Liu, Lin-Li Yao, Jiaofeng Wang, Danni Xiang, Jianxia Ma, Gansheng Zhang, Shan Zhang, Jun Li, Shu-Heng Jiang, Xiaona Hu, Jie Chen, Zhijun Bao
Int. J. Biol. Sci. 2023; 19(8): 2613-2629. doi:10.7150/ijbs.81498
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
LncRNA UCA1 Participates in De Novo Synthesis of Guanine Nucleotides in Bladder Cancer by Recruiting TWIST1 to Increase IMPDH1/2
Shan-Shan Liu, Jia-Shu Li, Mei Xue, Wen-Jing Wu, Xu Li, Wei Chen
Int. J. Biol. Sci. 2023; 19(8): 2599-2612. doi:10.7150/ijbs.82875
[Abstract] [Full text] [PDF] [PubMed] [PMC]

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