Global reach, higher impact
Review
Long Non-Coding RNAs: Potential Biomarkers and Targets for Hepatocellular Carcinoma Therapy and Diagnosis
Donghong Yuan, Yu Chen, Xiaobing Li, Jing Li, Yueshui Zhao, Jing Shen, Fukuan Du, Parham Jabbarzadeh Kaboli, Mingxing Li, Xu Wu, Huijiao Ji, Chi Hin Cho, Qinglian Wen, Wanping Li, Zhangang Xiao, Bo Chen
Int. J. Biol. Sci. 2021; 17(1): 220-235. doi:10.7150/ijbs.50730
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Review
Biological characteristics of IL-6 and related intestinal diseases
Yuexin Guo, Boya Wang, Tiantian Wang, Lei Gao, Ze-jun Yang, Fei-fei Wang, Hong-wei Shang, Rongxuan Hua, Jing-dong Xu
Int. J. Biol. Sci. 2021; 17(1): 204-219. doi:10.7150/ijbs.51362
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Research Paper
PRPF6 promotes androgen receptor/androgen receptor-variant 7 actions in castration-resistant prostate cancer cells
Wei Liu, Chunyu Wang, Shengli Wang, Kai Zeng, Shan Wei, Ning Sun, Ge Sun, Manlin Wang, Renlong Zou, Wensu Liu, Lin Lin, Huijuan Song, Zining Jin, Yue Zhao
Int. J. Biol. Sci. 2021; 17(1): 188-203. doi:10.7150/ijbs.50810
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Research Paper
MYC dysfunction modulates stemness and tumorigenesis in breast cancer
Yiqiu Liu, Chengjun Zhu, Lin Tang, Qin Chen, Nan Guan, Kun Xu, Xiaoxiang Guan
Int. J. Biol. Sci. 2021; 17(1): 178-187. doi:10.7150/ijbs.51458
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Review
Regulation of exosome production and cargo sorting
Hong Wei, Qi Chen, Li Lin, Chunli Sha, Taoqiong Li, Yueqin Liu, Xinming Yin, Yuhao Xu, Lu Chen, Wujiang Gao, Yuefeng Li, Xiaolan Zhu
Int. J. Biol. Sci. 2021; 17(1): 163-177. doi:10.7150/ijbs.53671
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Research Paper
Ferroptosis in a sarcopenia model of senescence accelerated mouse prone 8 (SAMP8)
Yan Huang, Beiling Wu, Dingzhu Shen, Jiulin Chen, Zhihua Yu, Chuan Chen
Int. J. Biol. Sci. 2021; 17(1): 151-162. doi:10.7150/ijbs.53126
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Review
The Emerging Roles of Autophagy-Related MicroRNAs in Cancer
Chan Shan, Xinzhe Chen, Hongjing Cai, Xiaodan Hao, Jing Li, Yinfeng Zhang, Jinning Gao, Zhixia Zhou, Xinmin Li, Cuiyun Liu, Peifeng Li, Kun Wang
Int. J. Biol. Sci. 2021; 17(1): 134-150. doi:10.7150/ijbs.50773
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Review
Genome-to-phenome research in rats: progress and perspectives
Amy L. Zinski, Shane Carrion, Jennifer J. Michal, Maria A. Gartstein, Raymond M. Quock, Jon F. Davis, Zhihua Jiang
Int. J. Biol. Sci. 2021; 17(1): 119-133. doi:10.7150/ijbs.51628
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Research Paper
Deciphering the genomic and lncRNA landscapes of aerobic glycolysis identifies potential therapeutic targets in pancreatic cancer
Li-Li Zhu, Zheng Wu, Rong-Kun Li, Xin Xing, Yong-Sheng Jiang, Jun Li, Ya-Hui Wang, Li-Peng Hu, Xu Wang, Wei-Ting Qin, Yong-Wei Sun, Zhi-Gang Zhang, Qin Yang, Shu-Heng Jiang
Int. J. Biol. Sci. 2021; 17(1): 107-118. doi:10.7150/ijbs.49243
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Review
SARS-CoV-2 variants evolved during the early stage of the pandemic and effects of mutations on adaptation in Wuhan populations
Annoor Awadasseid, Yanling Wu, Yoshimasa Tanaka, Wen Zhang
Int. J. Biol. Sci. 2021; 17(1): 97-106. doi:10.7150/ijbs.47827
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Review
The Regulatory Effect of SIRT1 on Extracellular Microenvironment Remodeling
Zhuo Wang, Wendong Guo, Fei Yi, Tingting Zhou, Xiaoman Li, Yanling Feng, Qiqiang Guo, Hongde Xu, Xiaoyu Song, Liu Cao
Int. J. Biol. Sci. 2021; 17(1): 89-96. doi:10.7150/ijbs.52619
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Review
Role of hydrogen sulfide donors in cancer development and progression
Ebenezeri Erasto Ngowi, Attia Afzal, Muhammad Sarfraz, Saadullah Khattak, Shams Uz Zaman, Nazeer Hussain Khan, Tao Li, Qi-Ying Jiang, Xin Zhang, Shao-Feng Duan, Xin-Ying Ji, Dong-Dong Wu
Int. J. Biol. Sci. 2021; 17(1): 73-88. doi:10.7150/ijbs.47850
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Review
A Multiple-Hit Hypothesis Involving Reactive Oxygen Species and Myeloperoxidase Explains Clinical Deterioration and Fatality in COVID-19
Pravin T Goud, David Bai, Husam M Abu-Soud
Int. J. Biol. Sci. 2021; 17(1): 62-72. doi:10.7150/ijbs.51811
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Research Paper
Eomesodermin in CD4+T cells is essential for Ginkgolide K ameliorating disease progression in experimental autoimmune encephalomyelitis
Sheng Chen, Juan Zhang, Wen-Bo Yu, Jing-Cong Zhuang, Wei Xiao, Zhi-Ying Wu, Bao-Guo Xiao
Int. J. Biol. Sci. 2021; 17(1): 50-61. doi:10.7150/ijbs.50041
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Review
βII spectrin (SPTBN1): biological function and clinical potential in cancer and other diseases
Panyu Yang, Yanyan Yang, Pin Sun, Yu Tian, Fang Gao, Chen Wang, Tingyu Zong, Min Li, Ying Zhang, Tao Yu, Zhirong Jiang
Int. J. Biol. Sci. 2021; 17(1): 32-49. doi:10.7150/ijbs.52375
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Research Paper
ACE2 Correlated With Immune Infiltration Serves As A Novel Prognostic Biomarker In Clear Cell Renal Cell Carcinoma: Implication For COVID-19
Wuping Yang, Lei Li, Kenan Zhang, Kaifang Ma, Haibiao Xie, Yanqing Gong, Jingcheng Zhou, Kan Gong
Int. J. Biol. Sci. 2021; 17(1): 20-31. doi:10.7150/ijbs.51969
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Editor-in-Chief: Chuxia Deng, PhD, Dean and Chair Professor,
Faculty of Health Sciences, University of Macau
Editor-in-Chief's Profile  Latest impact factor 4.858 according to 2020 release of JCR®. |
🆘 The global battle against SARS-CoV-2 and COVID-19: Special issue on Coronavirus disease https://www.ijbs.com/v16i10 |
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| Postdoctoral Fellowship and Associateship available in Faculty of Health Sciences (FHS),University of Macau ...full details |
| Journal of Genomics articles: Research Paper Research Paper Research Paper Short Research Paper |
Top cited papers:
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| The amyloid precursor protein plus presenilin-1 (APP/PS1) mice are a frequently-used model for Alzheimer's disease studies (AD). However, the data relevant to which proteins are involved in inflammatory mechanism are not sufficiently well-studied using the AD mouse model. Using behavioral studies, quantitative RT-PCR and Western-blot techniques, significant findings were determined by the expression of proteins involved in inflammation comparing APP/PS1 and Wild type mice. Increased GFAP expression could be associated with the elevation in number of reactive astrocytes.. ....details |
| Recently, interest in IL-15-differentiated cells has increased; however, the phenotypic definition of IL-15-differentiated bone marrow-derived cells (IL-15-DBMCs) is still under debate, particularly the generation of IFN-γ-producing innate cells such as premature NK (pre-mNK) cells, natural killer dendritic cells (NKDCs), interferon-producing killer dendritic cells (IKDCs), and type 1 innate lymphoid cells (ILC1s), all of which are IL-15-dependent. Here, we revisited the immunophenotypic characteristics of IFN-γ-producing IL-15-DBMCs and their functional role in the control of intracellular Mycobacterium tuberculosis (Mtb) infection.. ....details |
| Bone marrow-derived progenitor cell-mediated vasculogenesis is a key process for vascular repair and regeneration. However, the role of androgens in the mechanism of ischemia-induced vasculogenesis remains unclear. In this study, a gender-mismatch murine bone marrow transplant model was used to allow tissue tracking of transplanted cells. Bone marrow from 2-month-old male mice was transplanted into irradiated age-matched female recipients. Following the transplantation, ovariectomized female recipients were subjected to unilateral hindlimb ischemia and immediately implanted with either dihydrotestosterone (DHT) or placebo pellets. Laser Doppler perfusion imaging revealed that DHT significantly augmented blood flow recovery, with increased capillary density compared to placebo-treated female recipient controls.. ....details |
| In this review, we describe the current progresses of cancer related exosomes, including their biogenesis, molecular contents, biological functions, sources where they are derived from, and methods for their detection. We will also discuss the current exosomal biomarkers and the utilization of them for early diagnosis and prognostics in cancer. ... ...details |