Review
Respiratory syncytial virus: from pathogenesis to potential therapeutic strategies
Zifang Shang, Shuguang Tan, Dongli Ma
Int. J. Biol. Sci. 2021; 17(14): 4073-4091. doi:10.7150/ijbs.64762
[Abstract] [Full text] [PDF]

Review
The Hippo pathway: a renewed insight in the craniofacial diseases and hard tissue remodeling
Jun Chen, Jingyi Cheng, Cong Zhao, Boxuan Zhao, Jia Mi, Wenjie Li
Int. J. Biol. Sci. 2021; 17(14): 4060-4072. doi:10.7150/ijbs.63305
[Abstract] [Full text] [PDF]

Review
Post-Translational Modifications of PCNA in Control of DNA Synthesis and DNA Damage Tolerance-the Implications in Carcinogenesis
Siyi Zhang, Tingting Zhou, Zhuo Wang, Fei Yi, Chunlu Li, Wendong Guo, Hongde Xu, Hongyan Cui, Xiang Dong, Jingwei Liu, Xiaoyu Song, Liu Cao
Int. J. Biol. Sci. 2021; 17(14): 4047-4059. doi:10.7150/ijbs.64628
[Abstract] [Full text] [PDF]

Review
The Role of p38γ in Cancer: From review to outlook
Wentao Xu, Rui Liu, Ying Dai, Shaocheng Hong, Huke Dong, Hua Wang
Int. J. Biol. Sci. 2021; 17(14): 4036-4046. doi:10.7150/ijbs.63537
[Abstract] [Full text] [PDF]

Erratum
MiR-487a Promotes TGF-β1-induced EMT, the Migration and Invasion of Breast Cancer Cells by Directly Targeting MAGI2
Mengtao Ma, Miao He, Qian Jiang, Yuanyuan Yan, Shu Guan, Jing Zhang, Zhaojin Yu, Qiuchen Chen, Mingli Sun, Weifan Yao, Haishan Zhao, Feng Jin, Minjie Wei
Int. J. Biol. Sci. 2021; 17(14): 4034-4035. doi:10.7150/ijbs.67062
[Abstract] [Full text] [PDF]

Research Paper
Tubular cell-derived exosomal miR-150-5p contributes to renal fibrosis following unilateral ischemia-reperfusion injury by activating fibroblast in vitro and in vivo
Xiangjun Zhou, Sheng Zhao, Wei Li, Yuan Ruan, Run Yuan, Jinzhuo Ning, Kun Jiang, Jinna Xie, Xiaobin Yao, Haoyong Li, Chenglong Li, Ting Rao, Weimin Yu, Fan Cheng
Int. J. Biol. Sci. 2021; 17(14): 4021-4033. doi:10.7150/ijbs.62478
[Abstract] [Full text] [PDF]

Research Paper
PRG-1 relieves pain and depressive-like behaviors in rats of bone cancer pain by regulation of dendritic spine in hippocampus
Xingfeng Liu, Zhuo Xie, Site Li, Jingxin He, Song Cao, Zhi Xiao
Int. J. Biol. Sci. 2021; 17(14): 4005-4020. doi:10.7150/ijbs.59032
[Abstract] [Full text] [PDF]

Research Paper
The imbalance of PGD2-DPs pathway is involved in the type 2 diabetes brain injury by regulating autophagy
Yang Yang, Pu Xiang, Qi Chen, Ying Luo, Hong Wang, Huan Li, Lu Yang, Congli Hu, Jiahua Zhang, Yuke Li, Hui Xia, Zhihao Chen, Junqing Yang
Int. J. Biol. Sci. 2021; 17(14): 3993-4004. doi:10.7150/ijbs.60149
[Abstract] [Full text] [PDF]

Review
Enolase 1, a Moonlighting Protein, as a Potential Target for Cancer Treatment
Gan Qiao, Anguo Wu, Xiaoliang Chen, Ye Tian, Xiukun Lin
Int. J. Biol. Sci. 2021; 17(14): 3981-3992. doi:10.7150/ijbs.63556
[Abstract] [Full text] [PDF]

Research Paper
Long non-coding RNA MEG3 promotes cisplatin-induced nephrotoxicity through regulating AKT/TSC/mTOR-mediated autophagy
Xu Jing, Jinming Han, Junhao Zhang, Yi Chen, Juan Yuan, Jue Wang, Shiyong Neo, Shuijie Li, Xueyuan Yu, Jing Wu
Int. J. Biol. Sci. 2021; 17(14): 3968-3980. doi:10.7150/ijbs.58910
[Abstract] [Full text] [PDF]

Research Paper
COVID-19 disease and malignant cancers: The impact for the furin gene expression in susceptibility to SARS-CoV-2
Dabing Li, Xiaoyan Liu, Lianmei Zhang, Jiayue He, Xianmao Chen, Shuguang Liu, Jiewen Fu, Shangyi Fu, Hanchun Chen, Junjiang Fu, Jingliang Cheng
Int. J. Biol. Sci. 2021; 17(14): 3954-3967. doi:10.7150/ijbs.63072
[Abstract] [Full text] [PDF]

Research Paper
Lrp6 Genotype affects Individual Susceptibility to Nonalcoholic Fatty Liver Disease and Silibinin Therapeutic Response via Wnt/β-catenin-Cyp2e1 Signaling
Li-Jie Chen, Xiu-Xian Lin, Jing Guo, Ying Xu, Song-Xia Zhang, Dan Chen, Qing Zhao, Jian Xiao, Guang-Hui Lian, Shi-Fang Peng, Dong Guo, Hong Yang, Yan Shu, Hong-Hao Zhou, Wei Zhang, Yao Chen
Int. J. Biol. Sci. 2021; 17(14): 3936-3953. doi:10.7150/ijbs.63732
[Abstract] [Full text] [PDF]

Review
Role of mismatch repair in aging
Jie Wen, Yangyang Wang, Minghao Yuan, Zhenting Huang, Qian Zou, Yinshuang Pu, Bin Zhao, Zhiyou Cai
Int. J. Biol. Sci. 2021; 17(14): 3923-3935. doi:10.7150/ijbs.64953
[Abstract] [Full text] [PDF]

Research Paper
Deletion of Smad3 protects against C-reactive protein-induced renal fibrosis and inflammation in obstructive nephropathy
Yong-Ke You, Wei-Feng Wu, Xiao-Ru Huang, Hai-Di Li, Ye-Ping Ren, Jin-Cheng Zeng, Haiyong Chen, Hui Yao Lan
Int. J. Biol. Sci. 2021; 17(14): 3911-3922. doi:10.7150/ijbs.62929
[Abstract] [Full text] [PDF]

Research Paper
ADAM9 functions as a transcriptional regulator to drive angiogenesis in esophageal squamous cell carcinoma
Yu-Sen Lin, Ting-Ting Kuo, Chia-Chien Lo, Wei-Chung Cheng, Wei-Chao Chang, Guan-Chin Tseng, Shih-Ting Bai, Yu-Kai Huang, Chih-Ying Hsieh, Han-Shui Hsu, Yi-Fan Jiang, Chen-Yuan Lin, Liang-Chuan Lai, Xing-Guo Li, Yuh-Pyng Sher
Int. J. Biol. Sci. 2021; 17(14): 3898-3910. doi:10.7150/ijbs.65488
[Abstract] [Full text] [PDF]

Research Paper
The intraviral protein-protein interaction of SARS-CoV-2 reveals the key role of N protein in virus-like particle assembly
Minghai Chen, Chuang Yan, Fujun Qin, Luping Zheng, Xian-En Zhang
Int. J. Biol. Sci. 2021; 17(14): 3889-3897. doi:10.7150/ijbs.64977
[Abstract] [Full text] [PDF]

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