Int J Biol Sci 2011; 7(8):1203-1213. doi:10.7150/ijbs.7.1203
Photoactivation Studies of Zinc Porphyrin-Myoglobin System and Its Application for Light-Chemical Energy Conversion
1. Department of Biological Science and Technology, National Chiao Tung University, 30068, Hsin-Chu, Taiwan, Republic of China
2. Department of Applied Chemistry, National Chi Nan University, Puli, Nantou County, Taiwan, Republic of China
3. Department of Applied Chemistry and Institute of Molecular Science, National Chiao Tung University, Hsin-Chu, Taiwan, Republic of China
Chang CH, Hu YT, Lo CF, Luo L, Lin HM, Chang CH, Lin CY, Diau EWG, Wu TK. Photoactivation Studies of Zinc Porphyrin-Myoglobin System and Its Application for Light-Chemical Energy Conversion. Int J Biol Sci 2011; 7(8):1203-1213. doi:10.7150/ijbs.7.1203. Available from http://www.ijbs.com/v07p1203.htm
An artificial zinc porphyrin-myoglobin-based photo-chemical energy conversion system, consisting of ZnPP-Mb or ZnPE1-Mb as a photosensitizer, NADP+ as an electron acceptor, and triethanolamine as an electron donor, has been constructed to mimic photosystem I. The photoirradiated product is able to reduce a single-electron acceptor protein cytochrome c, but cannot catalyze the two-electron reduction of acetaldehyde by alcohol dehydrogenase, thus demonstrating a single electron transfer mechanism. Furthermore, the artificial system can bifunctionally promote oxidoredox reactions, depending on the presence or absence of a sacrificial electron donor, thus suggesting its potential application in electrochemical regeneration steps involved in chemical transformation and/or energy conversion.
Keywords: photoelectrochemical energy conversion, zinc protoporphyrin, myoglobin, oxidoredox reaction, biosensitizer