Int J Biol Sci 2020; 16(3):365-373. doi:10.7150/ijbs.39387 This issue


Precise hepatectomy in the intelligent digital era

Hao Chen1,2*, Yuchen He3*, Weidong Jia1,2✉

1. Department of Hepatic Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, HeFei, 230001, China
2. Anhui Province Key Laboratory of Hepatopancreatobiliary Surgery, HeFei, 230001, China
3. Xiangya School of Medicine, Central South University, ChangSha, 410008, China
* These authors contributed equally to this work.

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Chen H, He Y, Jia W. Precise hepatectomy in the intelligent digital era. Int J Biol Sci 2020; 16(3):365-373. doi:10.7150/ijbs.39387. Available from

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Graphic abstract

In the past 20 years, the concept of surgery has undergone profound changes. Surgical practice has shifted from emphasizing the complete elimination of lesions to achieving optimal rehabilitation in patients. Collaborative optimization of surgery consists of three core elements, removal of lesions, organ protection and injury close monitoring, and controlled surgical intervention. As a result, the traditional surgical paradigm has quietly transformed into a modern precision surgical paradigm. In this review, we summarized the latest breakthroughs and applications of precision medicine in liver surgery. In addition, we also outlined the progresses that have been made in precision liver surgery, the opportunities and challenges that may encountered in the future.

Keywords: liver surgery, digital medicine, big data, artificial intelligence