International Journal of Biological Sciences

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Volume 10 (7); 2014

Research Paper

Long Non-coding RNA URHC Regulates Cell Proliferation and Apoptosis via ZAK through the ERK/MAPK Signaling Pathway in Hepatocellular Carcinoma
Wei-Hua Xu, Jian-Bin Zhang, Zheng Dang, Xiao Li, Ti Zhou, Jie Liu, De-Sheng Wang, Wen-Jie Song, Ke-Feng Dou
Int. J. Biol. Sci. 2014; 10(7): 664-676. doi:10.7150/ijbs.8232
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Predicting Disease-Related Proteins Based on Clique Backbone in Protein-Protein Interaction Network
Lei Yang, Xudong Zhao, Xianglong Tang
Int. J. Biol. Sci. 2014; 10(7): 677-688. doi:10.7150/ijbs.8430
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Amoebozoa Possess Lineage-Specific Globin Gene Repertoires Gained by Individual Horizontal Gene Transfers
Jasmin Dröge, Dorota Buczek, Yutaka Suzuki, Wojciech Makałowski
Int. J. Biol. Sci. 2014; 10(7): 689-701. doi:10.7150/ijbs.8327
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Targeting the Sheddase Activity of ADAM17 by an Anti-ADAM17 Antibody D1(A12) Inhibits Head and Neck Squamous Cell Carcinoma Cell Proliferation and Motility via Blockage of Bradykinin Induced HERs Transactivation
Yanchao Huang, Nathan Benaich, Christopher Tape, Hang Fai Kwok, Gillian Murphy
Int. J. Biol. Sci. 2014; 10(7): 702-714. doi:10.7150/ijbs.9326
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Type-IV Antifreeze Proteins are Essential for Epiboly and Convergence in Gastrulation of Zebrafish Embryos
Qing Xiao, Jian-Hong Xia, Xiao-Juan Zhang, Zhi Li, Yang Wang, Li Zhou, Jian-Fang Gui
Int. J. Biol. Sci. 2014; 10(7): 715-732. doi:10.7150/ijbs.9126
[Abstract] [Full text] [PDF] [PubMed] [PMC]


MicroRNA-135a Inhibits Cell Proliferation by Targeting Bmi1 in Pancreatic Ductal Adenocarcinoma
Zheng Dang, Wei-hua Xu, Peng Lu, Nan Wu, Jie Liu, Bai Ruan, Liang Zhou, Wen-jie Song, Ke-feng Dou
Int. J. Biol. Sci. 2014; 10(7): 733-745. doi:10.7150/ijbs.8097
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Dimethyloxaloylglycine Improves Angiogenic Activity of Bone Marrow Stromal Cells in the Tissue-Engineered Bone
Hao Ding, Song Chen, Wen-Qi Song, You-Shui Gao, Jun-Jie Guan, Yang Wang, Yuan Sun, Chang-Qing Zhang
Int. J. Biol. Sci. 2014; 10(7): 746-756. doi:10.7150/ijbs.8535
[Abstract] [Full text] [PDF] [PubMed] [PMC]


A Novel Role of Exogenous Carbon Monoxide on Protecting Cardiac Function and Improving Survival against Sepsis via Mitochondrial Energetic Metabolism Pathway
Xu Wang, Weiting Qin, Xuefeng Qiu, Jie Cao, Dadong Liu, Bingwei Sun
Int. J. Biol. Sci. 2014; 10(7): 777-788. doi:10.7150/ijbs.9220
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Swainsonine Induces Apoptosis through Mitochondrial Pathway and Caspase Activation in Goat Trophoblasts
Yong Huang, Feng Dong, Qian Du, Hongling Zhang, Xiaomao Luo, Xiangjun Song, Xiaomin Zhao, Wenlong Zhang, Dewen Tong
Int. J. Biol. Sci. 2014; 10(7): 789-797. doi:10.7150/ijbs.9168
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Up-Regulated Lipocalin-2 in Pulmonary Hypertension Involving in Pulmonary Artery SMC Resistance to Apoptosis
Guoliang Wang, Xiaoyan Liu, Liukun Meng, Shenghua Liu, Li Wang, Jun Li, Chuanjue Cui, Jian Meng, Shengshou Hu, Yingjie Wei
Int. J. Biol. Sci. 2014; 10(7): 798-806. doi:10.7150/ijbs.9470
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Short Research Communication

Direct Evidence for Calcineurin Binding to the Exon-7 Loop of the Sodium-Bicarbonate Cotransporter NBCn1
Harindarpal S. Gill, Eric D. Roush, Lauren Dutcher, Samir Patel
Int. J. Biol. Sci. 2014; 10(7): 771-776. doi:10.7150/ijbs.9539
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

Recent Advances in Drug Repositioning for the Discovery of New Anticancer Drugs
Joong Sup Shim, Jun O. Liu
Int. J. Biol. Sci. 2014; 10(7): 654-663. doi:10.7150/ijbs.9224
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Targeting Histone Deacetylases for Cancer Therapy: From Molecular Mechanisms to Clinical Implications
Zhiming Li, Wei-Guo Zhu
Int. J. Biol. Sci. 2014; 10(7): 757-770. doi:10.7150/ijbs.9067
[Abstract] [Full text] [PDF] [PubMed] [PMC]