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Volume 10 (6); 2014

Editorial

Biological and Clinical Significance of Androgens and Androgen Receptor in Prostate Cancer
Shahriar Koochekpour
Int. J. Biol. Sci. 2014; 10(6): 652-653. doi:10.7150/ijbs.9576
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper

Conversion of Androgen Receptor Signaling From a Growth Suppressor in Normal Prostate Epithelial Cells to an Oncogene in Prostate Cancer Cells Involves a Gain of Function in c-Myc Regulation
Donald J. Vander Griend, Ivan V. Litvinov, John T. Isaacs
Int. J. Biol. Sci. 2014; 10(6): 627-642. doi:10.7150/ijbs.8756
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Androgen Receptor Mutations and Polymorphisms in African American Prostate Cancer
Shahriar Koochekpour, Erick Buckles, Mojgan Shourideh, SiYi Hu, Dhyan Chandra, Jovanny Zabaleta, Kristopher Attwood
Int. J. Biol. Sci. 2014; 10(6): 643-651. doi:10.7150/ijbs.8974
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

Targeting Androgen Receptor Action for Prostate Cancer Treatment: Does the Post-Receptor Level Provide Novel Opportunities?
Hannelore V. Heemers
Int. J. Biol. Sci. 2014; 10(6): 576-587. doi:10.7150/ijbs.8479
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Androgen Receptor as a Driver of Therapeutic Resistance in Advanced Prostate Cancer
Barbara Kahn, Joanne Collazo, Natasha Kyprianou
Int. J. Biol. Sci. 2014; 10(6): 588-595. doi:10.7150/ijbs.8671
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Roles for the Backdoor Pathway of Androgen Metabolism in Prostate Cancer Response to Castration and Drug Treatment
Michael V. Fiandalo, John Wilton, James L. Mohler
Int. J. Biol. Sci. 2014; 10(6): 596-601. doi:10.7150/ijbs.8780
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Beyond T and DHT - Novel Steroid Derivatives Capable of Wild Type Androgen Receptor Activation
Elahe A Mostaghel
Int. J. Biol. Sci. 2014; 10(6): 602-613. doi:10.7150/ijbs.8844
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Modulation of Androgen Receptor by FOXA1 and FOXO1 Factors in Prostate Cancer
Yu Zhao, Donald J. Tindall, Haojie Huang
Int. J. Biol. Sci. 2014; 10(6): 614-619. doi:10.7150/ijbs.8389
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Androgen Receptor Activation in Castration-Recurrent Prostate Cancer: The Role of Src-Family and Ack1 Tyrosine Kinases
Irwin H. Gelman
Int. J. Biol. Sci. 2014; 10(6): 620-626. doi:10.7150/ijbs.8264
[Abstract] [Full text] [PDF] [PubMed] [PMC]