International Journal of Biological Sciences

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Volume 12 (1); 2016

Research Paper


A Mechanobiology-based Algorithm to Optimize the Microstructure Geometry of Bone Tissue Scaffolds
Antonio Boccaccio, Antonio Emmanuele Uva, Michele Fiorentino, Luciano Lamberti, Giuseppe Monno
Int. J. Biol. Sci. 2016; 12(1): 1-17. doi:10.7150/ijbs.13158
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Excess Nitric Oxide Activates TRPV1-Ca2+-Calpain Signaling and Promotes PEST-dependent Degradation of Liver X Receptor α
Jin-Feng Zhao, Song-Kun Shyue, Tzong-Shyuan Lee
Int. J. Biol. Sci. 2016; 12(1): 18-29. doi:10.7150/ijbs.13549
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Hepatitis B Virus X Protein Upregulates hELG1/ ATAD5 Expression through E2F1 in Hepatocellular Carcinoma
Alip Ghosh, Suchandrima Ghosh, Debanjali Dasgupta, Amit Ghosh, Somenath Datta, Nilabja Sikdar, Simanti Datta, Abhijit Chowdhury, Soma Banerjee
Int. J. Biol. Sci. 2016; 12(1): 30-41. doi:10.7150/ijbs.12310
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Apigenin-7-O-β-D-(-6''-p-coumaroyl)-Glucopyranoside Treatment Elicits Neuroprotective Effect against Experimental Ischemic Stroke
Min Cai, Yulong Ma, Wei Zhang, Shiquan Wang, Ying Wang, Li Tian, Zhengwu Peng, Huaning Wang, Tan Qingrong
Int. J. Biol. Sci. 2016; 12(1): 42-52. doi:10.7150/ijbs.12275
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Reversine Increases the Plasticity of Long-Term Cryopreserved Fibroblasts to Multipotent Progenitor Cells through Activation of Oct4
Xiangchen Li, Yu Guo, Yaxin Yao, Jinlian Hua, Yuehui Ma, Changqing Liu, Weijun Guan
Int. J. Biol. Sci. 2016; 12(1): 53-62. doi:10.7150/ijbs.12199
[Abstract] [Full text] [PDF] [PubMed] [PMC]


uPA Attenuated LPS-induced Inflammatory Osteoclastogenesis through the Plasmin/PAR-1/Ca2+/CaMKK/AMPK Axis
Yosuke Kanno, Akira Ishisaki, Eri Kawashita, Hiromi Kuretake, Kanako Ikeda, Osamu Matsuo
Int. J. Biol. Sci. 2016; 12(1): 63-71. doi:10.7150/ijbs.12690
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Isovitexin Exerts Anti-Inflammatory and Anti-Oxidant Activities on Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting MAPK and NF-κB and Activating HO-1/Nrf2 Pathways
Hongming Lv, Zhenxiang Yu, Yuwei Zheng, Lidong Wang, Xiaofeng Qin, Genhong Cheng, Xinxin Ci
Int. J. Biol. Sci. 2016; 12(1): 72-86. doi:10.7150/ijbs.13188
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Retinoic Acid Induced-Autophagic Flux Inhibits ER-Stress Dependent Apoptosis and Prevents Disruption of Blood-Spinal Cord Barrier after Spinal Cord Injury
Yulong Zhou, Hongyu Zhang, Binbin Zheng, Libing Ye, Sipin Zhu, Noah R Johnson, Zhouguang Wang, Xiaojie Wei, Daqing Chen, Guodong Cao, Xiaobing Fu, Xiaokun Li, Hua-Zi Xu, Jian Xiao
Int. J. Biol. Sci. 2016; 12(1): 87-99. doi:10.7150/ijbs.13229
[Abstract] [Full text] [PDF] [PubMed] [PMC]


The Complete Mitochondrial Genome of two Tetragnatha Spiders (Araneae: Tetragnathidae): Severe Truncation of tRNAs and Novel Gene Rearrangements in Araneae
Zheng-Liang Wang, Chao Li, Wen-Yuan Fang, Xiao-Ping Yu
Int. J. Biol. Sci. 2016; 12(1): 109-119. doi:10.7150/ijbs.12358
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Photodynamic-therapy Activates Immune Response by disrupting Immunity Homeostasis of Tumor Cells, which Generates Vaccine for Cancer Therapy
Yuanhong Zheng, Guifang Yin, Vanminh Le, Anle Zhang, Siyu Chen, Xin Liang, Jianwen Liu
Int. J. Biol. Sci. 2016; 12(1): 120-132. doi:10.7150/ijbs.12852
[Abstract] [Full text] [PDF] [PubMed] [PMC]



Genome Wide Sampling Sequencing for SNP Genotyping: Methods, Challenges and Future Development
Zhihua Jiang, Hongyang Wang, Jennifer J. Michal, Xiang Zhou, Bang Liu, Leah C. Solberg Woods, Rita A. Fuchs
Int. J. Biol. Sci. 2016; 12(1): 100-108. doi:10.7150/ijbs.13498
[Abstract] [Full text] [PDF] [PubMed] [PMC]