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Volume 12 (2); 2016

Research Paper

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“DNA Binding Region” of BRCA1 Affects Genetic Stability through modulating the Intra-S-Phase Checkpoint
Takaaki Masuda, Xiaoling Xu, Emilios K. Dimitriadis, Tyler Lahusen, Chu-Xia Deng
Int. J. Biol. Sci. 2016; 12(2): 133-143. doi:10.7150/ijbs.14242
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Nucleophosmin Mutants Promote Adhesion, Migration and Invasion of Human Leukemia THP-1 Cells through MMPs Up-regulation via Ras/ERK MAPK Signaling
Jingrong Xian, Huiyuan Shao, Xianchun Chen, Shuaishuai Zhang, Jing Quan, Qin Zou, Hongjun Jin, Ling Zhang
Int. J. Biol. Sci. 2016; 12(2): 144-155. doi:10.7150/ijbs.13382
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Caspase-3/7-mediated Cleavage of β2-spectrin is Required for Acetaminophen-induced Liver Damage
Hye Jung Baek, Yong Min Lee, Tae Hyun Kim, Joo-Young Kim, Eun Jung Park, Kuniyoshi Iwabuchi, Lopa Mishra, Sang Soo Kim
Int. J. Biol. Sci. 2016; 12(2): 172-183. doi:10.7150/ijbs.13420
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Lysozyme Mutants Accumulate in Cells while Associated at their N-terminal Alpha-domain with the Endoplasmic Reticulum Chaperone GRP78/BiP
Yoshiki Kamada, Yusuke Nawata, Yasushi Sugimoto
Int. J. Biol. Sci. 2016; 12(2): 184-197. doi:10.7150/ijbs.13710
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Cyclosporine A Suppressed Glucose Oxidase Induced P53 Mitochondrial Translocation and Hepatic Cell Apoptosis through Blocking Mitochondrial Permeability Transition
Weihua Yu, Xiaodi Zhang, Jiangzheng Liu, Xin Wang, Shuang Li, Rui Liu, Nai Liao, Tao Zhang, Chunxu Hai
Int. J. Biol. Sci. 2016; 12(2): 198-209. doi:10.7150/ijbs.13716
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Diabetes Induced Changes in Podocyte Morphology and Gene Expression Evaluated Using GFP Transgenic Podocytes
Jianxiang Xu, Shirong Zheng, Patricia M. Kralik, Laxminarayanan Krishnan, Hui Huang, James B. Hoying, Lu Cai, Edward C. Carlson, Yi Tan, Paul N. Epstein
Int. J. Biol. Sci. 2016; 12(2): 210-218. doi:10.7150/ijbs.13057
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Long-term Stress with Hyperglucocorticoidemia-induced Hepatic Steatosis with VLDL Overproduction Is Dependent on both 5-HT2 Receptor and 5-HT Synthesis in Liver
Jihua Fu, Shaoxin Ma, Xin Li, Shanshan An, Tao Li, Keke Guo, Min Lin, Wei Qu, Shanshan Wang, Xinyue Dong, Xiaoyu Han, Ting Fu, Xinping Huang, Tianying Wang, Siyu He
Int. J. Biol. Sci. 2016; 12(2): 219-234. doi:10.7150/ijbs.13062
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Selective Regulation of MAPK Signaling Mediates RANKL-dependent Osteoclast Differentiation
Kyunghee Lee, Yeoun Ho Chung, Heejin Ahn, Hyunsoo Kim, Jaerang Rho, Daewon Jeong
Int. J. Biol. Sci. 2016; 12(2): 235-245. doi:10.7150/ijbs.13814
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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A Group of Novel Serum Diagnostic Biomarkers for Multidrug-Resistant Tuberculosis by iTRAQ-2D LC-MS/MS and Solexa Sequencing
Chong Wang, Chang-Ming Liu, Li-Liang Wei, Li-Ying Shi, Zhi-Fen Pan, Lian-Gen Mao, Xiao-Chen Wan, Ze-Peng Ping, Ting-Ting Jiang, Zhong-Liang Chen, Zhong-Jie Li, Ji-Cheng Li
Int. J. Biol. Sci. 2016; 12(2): 246-256. doi:10.7150/ijbs.13805
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Wheat Transcription Factor TaAREB3 Participates in Drought and Freezing Tolerances in Arabidopsis
Jingyi Wang, Qian Li, Xinguo Mao, Ang Li, Ruilian Jing
Int. J. Biol. Sci. 2016; 12(2): 257-269. doi:10.7150/ijbs.13538
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

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Recent Developments in Using Advanced Sequencing Technologies for the Genomic Studies of Lignin and Cellulose Degrading Microorganisms
Ayyappa kumar Sista Kameshwar, Wensheng Qin
Int. J. Biol. Sci. 2016; 12(2): 156-171. doi:10.7150/ijbs.13537
[Abstract] [Full text] [PDF] [PubMed] [PMC]