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Volume 7 (5); 2011

Research Paper

Overexpression of Grb2-associated Binder 2 in Human Lung Cancer
Xiu-Li Xu, Xia Wang, Zhao-Li Chen, Min Jin, Wu Yang, Guo-Fan Zhao, Jun-Wen Li
Int. J. Biol. Sci. 2011; 7(5): 496-504. doi:10.7150/ijbs.7.496
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Identification and Characterization of the Alternatively Spliced Nuclear Receptor Coactivator-6 Isoforms
Qingtian Li, Jianming Xu
Int. J. Biol. Sci. 2011; 7(5): 505-516. doi:10.7150/ijbs.7.505
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Varied Pathways of Stage IA Lung Adenocarcinomas Discovered by Integrated Gene Expression Analysis
Chengwen Chen, Xuping Fu, Deqiang Zhang, Yuan Li, Yi Xie, Yao Li, Yan Huang
Int. J. Biol. Sci. 2011; 7(5): 551-566. doi:10.7150/ijbs.7.551
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Alveolar Type II Cells Escape Stress Failure Caused by Tonic Stretch through Transient Focal Adhesion Disassembly
Xiao-Yang Liu, Xiao-Fei Chen, Yan-Hong Ren, Qing-Yuan Zhan, Chen Wang, Chun Yang
Int. J. Biol. Sci. 2011; 7(5): 588-599. doi:10.7150/ijbs.7.588
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Immunophenotyping at the Time of Diagnosis Distinguishes Two Groups of Nasopharyngeal Carcinoma Patients: Implications for Adoptive Immunotherapy
Jiang Li, Qiu-yan Chen, Haoyuan Mo, Yi-lan Zhang, Zhou-feng Huang, Yi-xin Zeng
Int. J. Biol. Sci. 2011; 7(5): 607-617. doi:10.7150/ijbs.7.607
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Expression, Purification and Characterization of A Novel Soluble Human Thymosin Alpha1 Concatemer Exhibited A Stronger Stimulation on Mice Lymphocytes Proliferation and Higher Anti-tumor Activity
Weina Li, Liqiang Song, Shouzhen Wu, Xiaochang Xue, Lu Zhang, Liqing He, Wei Han, Qing Wang, Rui Ling, Wei Zhang, Zhen Yan, Yingqi Zhang
Int. J. Biol. Sci. 2011; 7(5): 618-628. doi:10.7150/ijbs.7.618
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Coupling In vitro and In vivo Paradigm Reveals a Dose Dependent Inhibition of Angiogenesis Followed by Initiation of Autophagy by C6-Ceramide
Rishipal R. Bansode, Mohamed Ahmedna, Kurt R. Svoboda, Jack N. Losso
Int. J. Biol. Sci. 2011; 7(5): 629-644. doi:10.7150/ijbs.7.629
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Berberine Regulated Gck, G6pc, Pck1 and Srebp-1c Expression and Activated AMP-activated Protein Kinase in Primary Rat Hepatocytes
Yuebin Ge, Yan Zhang, Rui Li, Wei Chen, Yang Li, Guoxun Chen
Int. J. Biol. Sci. 2011; 7(5): 673-684. doi:10.7150/ijbs.7.673
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Short Research Communication

miR-148a Promoted Cell Proliferation by Targeting p27 in Gastric Cancer Cells
Shui-Long Guo1, Zheng Peng, Xue Yang, Kai-Ji Fan, Hui Ye, Zhen-Hua Li, Yan Wang, Xiao-Li Xu, Jun Li, You-Liang Wang, Yan Teng, Xiao Yang
Int. J. Biol. Sci. 2011; 7(5): 567-574. doi:10.7150/ijbs.7.567
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Study on the Characteristics of Contrast-Enhanced Ultrasound and Its Utility in Assessing the Microvessel Density in Ovarian Tumors or Tumor-Like Lesions
Junyan Wang, Faqin Lv, Xiang Fei, Qiuli Cui, Longxia Wang, Xuewen Gao, Zhixian Yuan, Qian Lin, Yali Lv, Aijun Liu
Int. J. Biol. Sci. 2011; 7(5): 600-606. doi:10.7150/ijbs.7.600
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Mechanism of AMPK Suppression of LXR-dependent Srebp-1c Transcription
Fuichi Yap, Lauren Craddock, Jian Yang
Int. J. Biol. Sci. 2011; 7(5): 645-650. doi:10.7150/ijbs.7.645
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Novel therapeutic Strategies for Targeting Liver Cancer Stem Cells
Naoki Oishi, Xin Wei Wang
Int. J. Biol. Sci. 2011; 7(5): 517-535. doi:10.7150/ijbs.7.517
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Signal Transducer and Activator of Transcription 3 in Liver Diseases: A Novel Therapeutic Target
Hua Wang, Fouad Lafdil, Xiaoni Kong, Bin Gao
Int. J. Biol. Sci. 2011; 7(5): 536-550. doi:10.7150/ijbs.7.536
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Mammalian Sirtuins and Energy Metabolism
Xiaoling Li, Nevzat Kazgan
Int. J. Biol. Sci. 2011; 7(5): 575-587. doi:10.7150/ijbs.7.575
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Dual Roles of Immune Cells and Their Factors in Cancer Development and Progression
Brian F. Zamarron, WanJun Chen
Int. J. Biol. Sci. 2011; 7(5): 651-658. doi:10.7150/ijbs.7.651
[Abstract] [Full text] [PDF] [PubMed] [PMC]

SRC-3 Has a Role in Cancer Other Than as a Nuclear Receptor Coactivator
Gang Ma, Yu Ren, Ke Wang, Jianjun He
Int. J. Biol. Sci. 2011; 7(5): 664-672. doi:10.7150/ijbs.7.664
[Abstract] [Full text] [PDF] [PubMed] [PMC]


The Heparan and Heparin Metabolism Pathway is Involved in Regulation of Fatty Acid Composition
Zhihua Jiang, Jennifer J. Michal, Xiao-Lin Wu, Zengxiang Pan, Michael D. MacNeil
Int. J. Biol. Sci. 2011; 7(5): 659-663. doi:10.7150/ijbs.7.659
[Abstract] [Full text] [PDF] [PubMed] [PMC]

miR-21 Promotes Keratinocyte Migration and Re-epithelialization During Wound Healing
Xue Yang, Jun Wang, Shui-Long Guo, Kai-Ji Fan, Jun Li, You-Liang Wang, Yan Teng, Xiao Yang
Int. J. Biol. Sci. 2011; 7(5): 685-690. doi:10.7150/ijbs.7.685
[Abstract] [Full text] [PDF] [PubMed] [PMC]