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Volume 20 (10); 2024

Research Papers

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Regulation of matrix reloading by tumor endothelial marker 1 protects against abdominal aortic aneurysm Yi-Kai Hong, Tsung-Lin Cheng, Chao-Kai Hsu, Fang-Tzu Lee, Bi-Ing Chang, Kuan-Chieh Wang, Lan-Yun Chang, Hua-Lin Wu, Chao-Han Lai Int. J. Biol. Sci. 2024; 20(10): 3691-3709. doi:10.7150/ijbs.93526 Full text PDF PubMed PMC


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Antirheumatic drug leflunomide attenuates atherosclerosis by regulating lipid metabolism and endothelial dysfunction via DHODH/AMPK signaling pathway Xinhai Jiang, Weizhi Wang, Lijuan Lei, Tingting Feng, Yang Hu, Peng Liu, Yining Li, Ren Sheng, Yuyan Zhang, Shunwang Li, Jing Zhang, Yuhao Zhang, Zheng-gen Jin, Zhuang Tian, Jiandong Jiang, Yanni Xu, Shuyi Si Int. J. Biol. Sci. 2024; 20(10): 3725-3741. doi:10.7150/ijbs.93465 Full text PDF PubMed PMC


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CHHM: a Manually Curated Catalogue of Human Histone Modifications Revealing Hotspot Regions and Unique Distribution Patterns Wendong Ma, Xiaofan Ding, Jiajia Xu, Terence Chuen Wai Poon Int. J. Biol. Sci. 2024; 20(10): 3760-3772. doi:10.7150/ijbs.95954 Full text PDF PubMed PMC


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Target deubiquitinase OTUB1 as a therapeatic strategy for BLCA via β-catenin/necroptosis signal pathway Yihao Liao, Jiaming Liang, Youzhi Wang, An Li, Wenbo Liu, Boqiang Zhong, Keke Wang, Diansheng Zhou, Tao Guo, Jianing Guo, Xi Yu, Ning Jiang Int. J. Biol. Sci. 2024; 20(10): 3784-3801. doi:10.7150/ijbs.94013 Full text PDF PubMed PMC


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siRNA-loaded folic acid-modified TPGS alleviate MASH via targeting ER stress sensor XBP1 and reprogramming macrophages Manman Zhu, Yong Cheng, Li Zuo, Bao Bin, Haiyuan Shen, Tao Meng, Zihao Wu, Peng Rao, Yue Tang, Shuojiao Li, Honghai Xu, Guoping Sun, Hua Wang, Guiyang Zhang, Jiatao Liu Int. J. Biol. Sci. 2024; 20(10): 3823-3841. doi:10.7150/ijbs.96113 Full text PDF PubMed PMC


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Single-cell and Spatial Transcriptomics Reveals Ferroptosis as The Most Enriched Programmed Cell Death Process in Hemorrhage Stroke-induced Oligodendrocyte-mediated White Matter Injury Lingui Gu, Hualin Chen, Ruxu Geng, Mingjiang Sun, Qinglei Shi, Yihao Chen, Jianbo Chang, Junji Wei, Wenbin Ma, Jiashun Xiao, Xinjie Bao, Renzhi Wang Int. J. Biol. Sci. 2024; 20(10): 3842-3862. doi:10.7150/ijbs.96262 Full text PDF PubMed PMC


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Participation of preovulatory follicles in the activation of primordial follicles in mouse ovaries Jingwen Zhang, Wenzhe Xia, Jiaqi Zhou, Shaogang Qin, Lin Lin, Ting Zhao, Huarong Wang, Chen Mi, Yifan Hu, Zixuan Chen, Tianhua Zhu, Xinyu Yang, Tuo Zhang, Guoliang Xia, Yuwen Ke, Chao Wang Int. J. Biol. Sci. 2024; 20(10): 3863-3880. doi:10.7150/ijbs.95020 Full text PDF PubMed PMC


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The Interaction of Calcium-Sensing Receptor with KIF11 Enhances Cisplatin Resistance in Lung Adenocarcinoma via BRCA1/cyclin B1 pathway Fuhao Wang, Xing Fu, Ming Chang, Tianzi Wei, Risheng Lin, Haibo Tong, Xiao Zhang, Runzhu Yuan, Zhiqing Zhou, Xin Huang, Wei Zhang, Wenmei Su, Yi Lu, Zhen Liang, Jian Zhang Int. J. Biol. Sci. 2024; 20(10): 3892-3910. doi:10.7150/ijbs.92046 Full text PDF PubMed PMC


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tRF-27 competitively Binds to G3BPs and Activates MTORC1 to Enhance HER2 Positive Breast Cancer Trastuzumab Tolerance Yaozhou He, Yincheng Liu, Jue Gong, Fan Yang, Chunxiao Sun, Xueqi Yan, Ningjun Duan, Yijia Hua, Tianyu Zeng, Ziyi Fu, Yan Liang, Wei Li, Xiang Huang, Jinhai Tang, Yongmei Yin Int. J. Biol. Sci. 2024; 20(10): 3923-3941. doi:10.7150/ijbs.87415 Full text PDF PubMed PMC


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Inhibition of PCSK9 enhances the anti-hepatocellular carcinoma effects of TCR-T cells and anti-PD-1 immunotherapy Weikang Xu, Minli Hu, Xinyu Lu, Yueqiong Lao, Na Ma, Yiyue Wang, Jing Li, Xingyuan Chen, Shiming Liu, Jing Liu, Wei Zhu, Hui Yang Int. J. Biol. Sci. 2024; 20(10): 3942-3955. doi:10.7150/ijbs.93668 Full text PDF PubMed PMC


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PKCα Induced the Generation of Extracellular Vesicles in Activated Platelets to Promote Breast Cancer Metastasis Jinghua Zhao, Huan Tian, Xiaona Zhao, Lan Lan, Huanhuan Liu, Yi Sun, Fengyan Yu Int. J. Biol. Sci. 2024; 20(10): 3956-3971. doi:10.7150/ijbs.89822 Full text PDF PubMed PMC


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KMT2D mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-induced regulatory T cell trafficking via FBXW7-NOTCH-MYC/TGF-β1 axis Qing-Xiao Liu, Yue Zhu, Hong-Mei Yi, Yi-Ge Shen, Li Wang, Shu Cheng, Peng-Peng Xu, Hai-Min Xu, Lu-Ting Zhou, Yao-Hui Huang, Chuan-Xin Huang, Di Fu, Meng-Meng Ji, Chao-Fu Wang, Wei-Li Zhao Int. J. Biol. Sci. 2024; 20(10): 3972-3985. doi:10.7150/ijbs.93349 Full text PDF PubMed PMC


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SUMO E3 ligase MUL1 inhibits lymph node metastasis of bladder cancer by mediating mitochondrial HSPA9 translocation Jilin Wu, Ming Huang, Wen Dong, Yuelong Chen, Qianghua Zhou, Qiang Zhang, Junjiong Zheng, Yeqing Liu, Yangjie Zhang, Sen Liu, Chenwei Yang, Siting Chen, Jian Huang, Tianxin Lin, Xu Chen Int. J. Biol. Sci. 2024; 20(10): 3986-4006. doi:10.7150/ijbs.98772 Full text PDF PubMed PMC


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Helicobacter pylori promotes gastric cancer through CagA-mediated mitochondrial cholesterol accumulation by targeting CYP11A1 redistribution Zhijun Zhang, Hongxin Huang, Zetian Chen, Mengpei Yan, Chen Lu, Zekuan Xu, Zheng Li Int. J. Biol. Sci. 2024; 20(10): 4007-4028. doi:10.7150/ijbs.96425 Full text PDF PubMed PMC


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Nephron-Specific Lin28A Overexpression Triggers Severe Inflammatory Response and Kidney Damage Anna Futorian, Leah Armon, Hiba Waldman Ben-Asher, Irit Shoval, Inbal Hazut, Ariel Munitz, Achia Urbach Int. J. Biol. Sci. 2024; 20(10): 4044-4054. doi:10.7150/ijbs.97434 Full text PDF PubMed PMC


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NRF2-HIF2α Signaling Attenuates Endothelial Cell Senescence and Maintains Intercellular Junctions in Diabetes Jian Shen, Yifan Lai, Yaner Lu, Yabin Liu, Jinlong Zhang, Yan Wu, Yunan Pan, Haibo Chen, Qiyue Gao, Qucheng Wei, Yuwen Chen, Jian Ye, Yinuo Lin, Bingchen Liu, Jun Jiang, Jinliang Nan Int. J. Biol. Sci. 2024; 20(10): 4055-4073. doi:10.7150/ijbs.96719 Full text PDF PubMed PMC


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Catalpol attenuates hepatic glucose metabolism disorder and oxidative stress in triptolide-induced liver injury by regulating the SIRT1/HIF-1α pathway Weijue Nie, Hong Zhu, Xin Sun, Jie Zhou, Heng Xu, Zhichao Yu, Minghao Lu, Baoping Jiang, Lingling Zhou, Xueping Zhou Int. J. Biol. Sci. 2024; 20(10): 4077-4097. doi:10.7150/ijbs.97362 Full text PDF PubMed PMC

Reviews

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Lipid homeostasis in diabetic kidney disease Ying Wang, Tongtong Liu, Yun Wu, Lin Wang, Shaowei Ding, Baoluo Hou, Hailing Zhao, Weijing Liu, Ping Li Int. J. Biol. Sci. 2024; 20(10): 3710-3724. doi:10.7150/ijbs.95216 Full text PDF PubMed PMC


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Clinical Implementation of Rare and Novel DPYD Variants for Personalizing Fluoropyrimidine Treatment: Challenges and Opportunities Elena De Mattia, Noemi Milan, Yehuda G. Assaraf, Giuseppe Toffoli, Erika Cecchin Int. J. Biol. Sci. 2024; 20(10): 3742-3759. doi:10.7150/ijbs.97686 Full text PDF PubMed PMC


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Ferroptosis: the balance between death and survival in colorectal cancer Shiying Fan, Lujia Zhou, Wenjie Zhang, Daorong Wang, Dong Tang Int. J. Biol. Sci. 2024; 20(10): 3773-3783. doi:10.7150/ijbs.96828 Full text PDF PubMed PMC


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Crosstalk of ubiquitin system and non-coding RNA in fibrosis Huamin Zhang, Yutong Zhou, Canhua Jiang, Ni Jian, Jie Wang Int. J. Biol. Sci. 2024; 20(10): 3802-3822. doi:10.7150/ijbs.93644 Full text PDF PubMed PMC


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Comprehensive review on the novel immunotherapy target: Leucine-rich repeat-containing 8A/volume-regulated anion channel Yaohua Hu, Jing Qin, Yifan Ma, Runze Yang, Xinyu Liu, Changhong Shi Int. J. Biol. Sci. 2024; 20(10): 3881-3891. doi:10.7150/ijbs.95933 Full text PDF PubMed PMC


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Using Combination therapy to overcome diverse challenges of Immune Checkpoint Inhibitors treatment Racheli Birnboim-Perach, Itai Benhar Int. J. Biol. Sci. 2024; 20(10): 3911-3922. doi:10.7150/ijbs.93697 Full text PDF PubMed PMC


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Helicobacter pylori Outer Membrane Vesicles: Biogenesis, Composition, and Biological Functions Jiao Li, Tingting Liao, Eng Guan Chua, Mingming Zhang, Yalin Shen, Xiaona Song, Barry J. Marshall, Mohammed Benghezal, Hong Tang, Hong Li Int. J. Biol. Sci. 2024; 20(10): 4029-4043. doi:10.7150/ijbs.94156 Full text PDF PubMed PMC


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Exosomes: Emerging Insights into the Progression of Pancreatic Cancer Xulin Zhou, Yongmin Yan, Ye Shen, Min Xu, Wenrong Xu Int. J. Biol. Sci. 2024; 20(10): 4098-4113. doi:10.7150/ijbs.97076 Full text PDF PubMed PMC

Commentary

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Innovative Insights into Ferroptosis in Oligodendrocytes Following Intracerebral Hemorrhage: Implications for Neuroprotection and Therapeutic Strategies Fangming Liu, Guohua Wang Int. J. Biol. Sci. 2024; 20(10): 4074-4076. doi:10.7150/ijbs.100754 Full text PDF PubMed PMC

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