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Volume 12 (5); 2016

Research Paper


Ebselen Is a Potential Anti-Osteoporosis Agent by Suppressing Receptor Activator of Nuclear Factor Kappa-B Ligand-Induced Osteoclast Differentiation In vitro and Lipopolysaccharide-Induced Inflammatory Bone Destruction In vivo
Jong Min Baek, Ju-Young Kim, Kwon-Ha Yoon, Jaemin Oh, Myeung Su Lee
Int. J. Biol. Sci. 2016; 12(5): 478-488. doi:10.7150/ijbs.13815
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Phylogenetic inference of calyptrates, with the first mitogenomes for Gasterophilinae (Diptera: Oestridae) and Paramacronychiinae (Diptera: Sarcophagidae)
Dong Zhang, Liping Yan, Ming Zhang, Hongjun Chu, Jie Cao, Kai Li, Defu Hu, Thomas Pape
Int. J. Biol. Sci. 2016; 12(5): 489-504. doi:10.7150/ijbs.12148
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Transcriptional Reactivation of OTX2, RX1 and SIX3 during Reprogramming Contributes to the Generation of RPE Cells from Human iPSCs
Peng Li, Xiaofeng Sun, Zhizhong Ma, Yinan Liu, Ying Jin, Ruimin Ge, Limin Hao, Yanling Ma, Shuo Han, Haojie Sun, Mingzhi Zhang, Ruizhi Li, Tao Li, Li Shen
Int. J. Biol. Sci. 2016; 12(5): 505-517. doi:10.7150/ijbs.14212
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Glycogen Synthase Kinase 3β Influences Injury Following Cerebral Ischemia/Reperfusion in Rats
Yixin Li, Jin Zhu, Yuanling Liu, Xi Chen, Shipeng Lei, Lingyu Li, Beibei Jiang, Li Tan, Shanshan Yu, Yong Zhao
Int. J. Biol. Sci. 2016; 12(5): 518-531. doi:10.7150/ijbs.13918
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Upregulation of the Non-Coding RNA OTUB1-isoform 2 Contributes to Gastric Cancer Cell Proliferation and Invasion and Predicts Poor Gastric Cancer Prognosis
Yi-qin Wang, Qiong-yan Zhang, Wei-wei Weng, Yong Wu, Yu-si Yang, Chen Shen, Xiao-Chen Chen, Lei Wang, Kai-jing Liu, Mi-die Xu, Wei-qi Sheng
Int. J. Biol. Sci. 2016; 12(5): 545-557. doi:10.7150/ijbs.13540
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Direct Reprogramming of Human Amniotic Fluid Stem Cells by OCT4 and Application in Repairing of Cerebral Ischemia Damage
Mingde Qin, Ruihua Chen, Hong Li, Hansi Liang, Qun Xue, Fang Li, Ying Chen, Xueguang Zhang
Int. J. Biol. Sci. 2016; 12(5): 558-568. doi:10.7150/ijbs.11051
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Dysregulation of the Low-Density Lipoprotein Receptor Pathway Is Involved in Lipid Disorder-Mediated Organ Injury
Yang Zhang, Kun Ling Ma, Xiong Zhong Ruan, Bi Cheng Liu
Int. J. Biol. Sci. 2016; 12(5): 569-579. doi:10.7150/ijbs.14027
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Methacryloxylethyl Cetyl Ammonium Chloride Induces DNA Damage and Apoptosis in Human Dental Pulp Cells via Generation of Oxidative Stress
Yang Jiao, Sai Ma, Yirong Wang, Jing Li, Lequn Shan, Jinlong Sun, Jihua Chen
Int. J. Biol. Sci. 2016; 12(5): 580-593. doi:10.7150/ijbs.14578
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Revealing the Effects of the Herbal Pair of Euphorbia kansui and Glycyrrhiza on Hepatocellular Carcinoma Ascites with Integrating Network Target Analysis and Experimental Validation
Yanqiong Zhang, Ya Lin, Haiyu Zhao, Qiuyan Guo, Chen Yan, Na Lin
Int. J. Biol. Sci. 2016; 12(5): 594-606. doi:10.7150/ijbs.14151
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Ecological Trade-offs between Migration and Reproduction Are Mediated by the Nutrition-Sensitive Insulin-Signaling Pathway
Xinda Lin, Yun Yao, Bo Wang, Douglas J. Emlen, Laura Corley Lavine
Int. J. Biol. Sci. 2016; 12(5): 607-616. doi:10.7150/ijbs.14802
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Modeling Energy Dynamics in Mice with Skeletal Muscle Hypertrophy Fed High Calorie Diets
Nichole D. Bond, Juen Guo, Kevin D. Hall, Alexandra C. McPherron
Int. J. Biol. Sci. 2016; 12(5): 617-630. doi:10.7150/ijbs.13525
[Abstract] [Full text] [PDF] [PubMed] [PMC]



Mitochondrial Stat3, the Need for Design Thinking
Rui Yang, Mercedes Rincon
Int. J. Biol. Sci. 2016; 12(5): 532-544. doi:10.7150/ijbs.15153
[Abstract] [Full text] [PDF] [PubMed] [PMC]