International Journal of Biological Sciences

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ISSN 1449-2288

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Volume 14 (12); 2018

Research Papers

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Polyclonal Rabbit Anti-Cancer-Associated Fibroblasts Globulins Induce Cancer Cells Apoptosis and Inhibit Tumor Growth
Xiuying Li, Fengchang Huang, Xiaoyu Xu, Shuenqin Hu
Int. J. Biol. Sci. 2018; 14(12): 1621-1629. doi:10.7150/ijbs.26520
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Epigenetic alterations of a novel antioxidant gene SLC22A3 predispose susceptible individuals to increased risk of esophageal cancer
Ji-Xian Xiong, Yan-Song Wang, Jingyi Sheng, Di Xiang, Tu-Xiong Huang, Bin-Bin Tan, Cui-Mian Zeng, Hua-Hui Li, Jiao Yang, Stephen J. Meltzer, Yuriko Mori, Yan-Ru Qin, Xin-Yuan Guan, Li Fu
Int. J. Biol. Sci. 2018; 14(12): 1658-1668. doi:10.7150/ijbs.28482
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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BERMP: a cross-species classifier for predicting m6A sites by integrating a deep learning algorithm and a random forest approach
Yu Huang, Ningning He, Yu Chen, Zhen Chen, Lei Li
Int. J. Biol. Sci. 2018; 14(12): 1669-1677. doi:10.7150/ijbs.27819
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The Pathogenesis of Atherosclerosis Based on Human Signaling Networks and Stem Cell Expression Data
Wan Li, Hao Huang, Lei Li, Li Wang, Yong Li, Yahui Wang, Shanshan Guo, Liansheng Li, Donghua Wang, Yuehan He, Lina Chen
Int. J. Biol. Sci. 2018; 14(12): 1678-1685. doi:10.7150/ijbs.27896
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Paired box 5 is a novel marker of breast cancers that is frequently downregulated by methylation
Xia Li, Jianbo Huang, Xinrong Luo, Dejuan Yang, Xuedong Yin, Weiyan Peng, Can Bi, Guosheng Ren, Tingxiu Xiang
Int. J. Biol. Sci. 2018; 14(12): 1686-1695. doi:10.7150/ijbs.27599
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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GLP-1 treatment protects endothelial cells from oxidative stress-induced autophagy and endothelial dysfunction
Xiangsheng Cai, Miaoqin She, Mingyu Xu, Huiying Chen, Jingjing Li, Xinglu Chen, Dianpeng Zheng, Jun Liu, Shangliang Chen, Jianbin Zhu, Xiaosong Xu, Ruiying Li, Jinlong Li, Shaolian Chen, Xiaorong Yang, Hongwei Li
Int. J. Biol. Sci. 2018; 14(12): 1696-1708. doi:10.7150/ijbs.27774
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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TGF-β/SMAD4-Regulated LncRNA-LINP1 Inhibits Epithelial-Mesenchymal Transition in Lung Cancer
Chong Zhang, Yajing Hao, Yanxiao Wang, Jiaqian Xu, Yan Teng, Xiao Yang
Int. J. Biol. Sci. 2018; 14(12): 1715-1723. doi:10.7150/ijbs.27197
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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TFmapper: A Tool for Searching Putative Factors Regulating Gene Expression Using ChIP-seq Data
Jianming Zeng, Gang Li
Int. J. Biol. Sci. 2018; 14(12): 1724-1731. doi:10.7150/ijbs.28850
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The small molecule NSM00191 specifically represses the TNF-α/NF-кB axis in foot and ankle rheumatoid arthritis
Xiaodong Wen, Xun Chen, Xiaojun Liang, Hongmou Zhao, Yi Li, Xiangxiang Sun, Jun Lu
Int. J. Biol. Sci. 2018; 14(12): 1732-1744. doi:10.7150/ijbs.24232
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Inhibition of Estrogen Signaling Reduces the Incidence of BRCA1-associated Mammary Tumor Formation
Hye Jung Baek, Sun Eui Kim, Eun Kyung Choi, Jong Kwang Kim, Dong Hoon Shin, Eun Jung Park, Tae Hyun Kim, Joo-Young Kim, Kwang Gi Kim, Chu-Xia Deng, Sang Soo Kim
Int. J. Biol. Sci. 2018; 14(12): 1755-1768. doi:10.7150/ijbs.28142
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Reviews

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Extracellular Vesicles: Potential Participants in Circadian Rhythm Synchronization
Shi-Cong Tao, Shang-Chun Guo
Int. J. Biol. Sci. 2018; 14(12): 1610-1620. doi:10.7150/ijbs.26518
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The Biological Roles of Translation Initiation Factor 3b
Xuefei Feng, Juan Li, Peijun Liu
Int. J. Biol. Sci. 2018; 14(12): 1630-1635. doi:10.7150/ijbs.26932
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Role of canonical Hedgehog signaling pathway in liver
Lili Gao, Zhenya Zhang, Peng Zhang, Minghua Yu, Tao Yang
Int. J. Biol. Sci. 2018; 14(12): 1636-1644. doi:10.7150/ijbs.28089
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Cardiac fibrosis: new insights into the pathogenesis
Zhen-Guo Ma, Yu-Pei Yuan, Hai-Ming Wu, Xin Zhang, Qi-Zhu Tang
Int. J. Biol. Sci. 2018; 14(12): 1645-1657. doi:10.7150/ijbs.28103
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Alternative polyadenylation analysis in animals and plants: newly developed strategies for profiling, processing and validation
Yunqi Zhang, Shane A. Carrion, Yangzi Zhang, Xiaohui Zhang, Amy L. Zinski, Jennifer J. Michal, Zhihua Jiang
Int. J. Biol. Sci. 2018; 14(12): 1709-1714. doi:10.7150/ijbs.27168
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Targeting phosphodiesterase 4 as a potential therapeutic strategy for enhancing neuroplasticity following ischemic stroke
Haitao Wang, Uma Gaur, Jiao Xiao, Bingtian Xu, Jiangping Xu, Wenhua Zheng
Int. J. Biol. Sci. 2018; 14(12): 1745-1754. doi:10.7150/ijbs.26230
[Abstract] [Full text] [PDF] [PubMed] [PMC]