Int J Biol Sci 2007; 3(1):8-11. doi:10.7150/ijbs.3.8 This issue

Short Research Communication

Gamma Protocadherin Expression in the Embryonic Chick Nervous System

Kenneth D. Cronin, Anthony A. Capehart

Department of Biology, East Carolina University, Greenville, North Carolina 27858, USA

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Citation:
Cronin KD, Capehart AA. Gamma Protocadherin Expression in the Embryonic Chick Nervous System. Int J Biol Sci 2007; 3(1):8-11. doi:10.7150/ijbs.3.8. Available from https://www.ijbs.com/v03p0008.htm

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Abstract

Protocadherin γ (pcdh-γ) family expression was examined in the embryonic chick central nervous system by in situ hybridization. Transcripts were visualized in discrete regions of fore-, mid-, and hindbrain at stages 23 and 25 and in spinal cord and optic lobe at stages 27 and 43, respectively. Results suggest that pcdh-γ may function cooperatively with other cell adhesion molecules in neuronal differentiation and establishment of neural networks in several areas of the developing brain, particularly regions involved in visual processing.

Keywords: cadherin, cell adhesion, central nervous system, chick embryo, neural development, protocadherin