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Volume 22 (11); 2026

Research Papers

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Cholesterol Overload Drives Hepatic Steatosis by Inhibiting OGT-dependent PPARα O-GlcNAcylation and Transactivation Rui Guo, Yanhui Li, Qinchao Ding, Chad Slawson, Udayan Apte, Yuwei Jiang, Xiaobing Dou, Songtao Li, Zhenyuan Song Int. J. Biol. Sci. 2026; 22(11): 5615-5633. doi:10.7150/ijbs.135054 Full text PDF


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The TRPM7 inhibitor carvacrol suppresses angiogenesis and vasculogenic mimicry in triple-negative breast cancer Tianci Tang, Na Zhao, Moqin Qiu, Luisa Müller, Michael D. Menger, Vladimir Chubanov, Thomas Gudermann, Gabriela Krasteva-Christ, Matthias W. Laschke, Yuan Gu Int. J. Biol. Sci. 2026; 22(11): 5634-5658. doi:10.7150/ijbs.130027 Full text PDF


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Targeting the exosomal CaMK2A-ZDHHC3-GPX4 pathway reprograms tumor-associated macrophages and enhances anti-PD-1/PD-L1 immunotherapy in gastric cancer Zetian Chen, Hongxin Huang, Yikai Shen, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Tianlu Jiang, Zekuan Xu, Zheng Li Int. J. Biol. Sci. 2026; 22(11): 5659-5684. doi:10.7150/ijbs.128976 Full text PDF


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Role of WDR66 in Stemness, Therapy Resistance and Tumor microenvironment modulation in Head and Neck Cancer Laura Sanchez-Diaz, Asuncion Espinosa-Sánchez A, Amancio Carnero Int. J. Biol. Sci. 2026; 22(11): 5685-5705. doi:10.7150/ijbs.130010 Full text PDF


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PFKFB3 Mediated Glycolytic Reprogramming Drives Vascular Endothelial Injury Under Chronic Intermittent Hypoxia Shi Qi Li, Yi Wang, Liu Zhang, Ya Ru Yan, Fang Ying Lu, Xi Xi Chen, Ying Ni Lin, Jun Qi Lin, Jian Ping Zhou, Li Ming Lu, Qing Yun Li Int. J. Biol. Sci. 2026; 22(11): 5735-5753. doi:10.7150/ijbs.129280 Full text PDF

Review

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Copper-Iron Cell Death Axis: Mechanistic Crosstalk, Disease Implications and an Integrated Metallo-Redox-Metabolic Framework HaoQi Huang, YuLu Chen, Yi Lu, ZiLong Yuan, Ahmed Zahoor, LiPing Ren, YuanYuan Luo, BaoCai Zhong, Jian Huang, Hui Chen, Lin Ning Int. J. Biol. Sci. 2026; 22(11): 5706-5734. doi:10.7150/ijbs.132221 Full text PDF

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