International Journal of Biological Sciences
ISSN: 1449-2288
Global reach, higher impactVolume 21 (6); 2025
Research Papers
Integrin β3-mediated platelet extracellular vesicle adhesion facilitates vascular smooth muscle cell dysfunction in postinjury intimal hyperplasia
Fei Zhuang, Zhi-tong Liu, Guo Zhou, Feng Liang, Ying-hua Wang, Long Chen, Wei-feng Zhang, Ling-hong Shen, Yan-qiao Lu, Huan-huan Huo, Xin Shi, Liang Fang, Ben He
Int. J. Biol. Sci. 2025; 21(6): 2380-2395. doi:10.7150/ijbs.101391
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PPARG Activation of Fatty Acid Metabolism Drives Resistance to Anti-HER2 Therapies in HER2-Positive Breast Cancer
Min Xiong, Douwaner Liu, Xuliren Wang, Hengyu Ren, Weiru Chi, Bingqiu Xiu, Qi Zhang, Jiayu Zhang, Liyi Zhang, Zehao Wang, Ming Chen, Jingyan Xue, Yayun Chi, Jiong Wu
Int. J. Biol. Sci. 2025; 21(6): 2396-2414. doi:10.7150/ijbs.99275
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Dual-specificity tyrosine-regulated kinase 4 modulates the STAT3-FOS signaling axis to inhibit hepatitis B virus replication via autophagy
Jiaqi Xu, Xianhuang Zeng, Junsong Huang, Shuangshuang Ma, Kun Li, Siqi Yang, Wajeeha Naz, Tanzeel Yousaf, Sen Yuan, Yang Liu, Jing Zhang, Chaozhi Liu, Chenyi Liu, Zixu Zhai, Mingxiong Guo, Guihong Sun
Int. J. Biol. Sci. 2025; 21(6): 2415-2429. doi:10.7150/ijbs.105447
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Cardiovascular Mettl3 Deficiency Causes Congenital Cardiac Defects and Postnatal Lethality in Mice
Qianqian Feng, Lihua Qi, Jiaqi Huang, Zhigang Dong, Fang Yu, Jing Zhang, Jun Zhan, Hongquan Zhang, Wengong Wang, Yong Zhou, Zhongzhou Yang, Yuan Zhou, Wei Kong, Yi Fu
Int. J. Biol. Sci. 2025; 21(6): 2430-2445. doi:10.7150/ijbs.100941
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A Novel Mouse Model of Depression: Advantages in Immune Research and Clinical Translation
Jing Xiong, Xian-Qiang Zhang, Ji-Tao Li, Chi Ren, Tian Shen, Yun-Ai Su, Tian-Mei Si
Int. J. Biol. Sci. 2025; 21(6): 2446-2461. doi:10.7150/ijbs.104950
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The SGK3/GSK3β/β-catenin signaling promotes breast cancer stemness and confers resistance to alpelisib therapy
Tingting Kang, Yuanfang Wang, Yaxin Jiang, Shunjie Chen, Na Lin, Minyan Guo, Haotu Zhu, Di Tang, Xiaofan Ding, Mian He
Int. J. Biol. Sci. 2025; 21(6): 2462-2475. doi:10.7150/ijbs.104850
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PROTAC-Surufatinib Suppresses Pancreatic Neuroendocrine Neoplasms Progression by Inducing Ferroptosis through Inhibiting WNT/β-catenin Pathway Mediated by HMOX1
Bingyan Xue, Lijun Yan, Mujie Ye, Danyang Gu, Jianqiang Qian, Na He, Ping Hu, Feiyu Lu, Xintong Lu, Min Liu, Lin Xu, Jianan Bai, Yan Wang, Guoqin Zhu, Qiyun Tang
Int. J. Biol. Sci. 2025; 21(6): 2476-2492. doi:10.7150/ijbs.106357
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Antcin K ameliorates cardiotoxin-induced skeletal muscle injury and inflammation via IL-10 regulation
Ting-Kuo Chang, Lin-Chu Huang, Yueh-Hsiung Kuo, Chun-Hao Tsai, Hsien-Te Chen, Yi-Syuan Wu, Chih-Hsin Tang, Chen-Ming Su
Int. J. Biol. Sci. 2025; 21(6): 2493-2507. doi:10.7150/ijbs.107343
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HDC/histamine Signaling Axis Drives Macrophage Reprogramming to Promote Angiogenesis in Hindlimb-Ischemic Mice
Dili Sun, Jianfu Zhu, Gaofeng Zeng, Xiyang Yang, Xiaowei Zhu, Diyaerjiang Aierken, Zhaocheng Shi, Suling Ding, Junbo Ge, Hai Hu, Xiangdong Yang
Int. J. Biol. Sci. 2025; 21(6): 2508-2530. doi:10.7150/ijbs.105148
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