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Volume 19 (8); 2023

Research Papers

The deubiquitinase UCHL1 negatively controls osteoclastogenesis by regulating TAZ/NFATC1 signalling
Zhenhua Feng, Siyue Tao, Zhaobo Huang, Bingjie Zheng, Xiangxi Kong, Yufeng Xiang, Qibin Zhang, Haixin Song, Zhikun Xu, Xiaoan Wei, Fengdong Zhao, Jian Chen
Int. J. Biol. Sci. 2023; 19(8): 2319-2332. doi:10.7150/ijbs.82152
Abstract Full text PDF PubMed PMC

Upregulated Long Non-coding RNA Lnc-MRPL39-2:1 Induces the Growth and Invasion of Nasopharyngeal Carcinoma by Binding to HuR and Stabilizing β-Catenin mRNA
Yunhong Tian, Meiling Ai, Chunshan Liu, Yuchao Wu, Muhammad Khan, Baiyao Wang, Huidong Long, Chunyue Huang, Jie Lin, Anan Xu, Rong Li, Bohong Cen, Wenze Qiu, Guofeng Xie, Yawei Yuan
Int. J. Biol. Sci. 2023; 19(8): 2349-2365. doi:10.7150/ijbs.79115
Abstract Full text PDF PubMed PMC

Inhibition of JNK/c-Jun-ATF2 Overcomes Cisplatin Resistance in Liver Cancer through down-Regulating Galectin-1
Fan Yang, Mengzhu Li, Duo Xu, Zebo Jiang, Hailong Jiang, Yitai Xiao, Chaoming Mei, Meilin Yang, Congmin Chen, Bin Zhou, Bailiang He, Hong Shan, Pengfei Pang, Dan Li
Int. J. Biol. Sci. 2023; 19(8): 2366-2381. doi:10.7150/ijbs.79163
Abstract Full text PDF PubMed PMC

Enhancement of Zyxin Promotes Skin Fibrosis by Regulating FAK/PI3K/AKT and TGF-β Signaling Pathways via Integrins
Yan Huang, Han Zhao, Yuting Zhang, Yulong Tang, Xiangguang Shi, Shuai Jiang, Weilin Pu, Jing Liu, Yanyun Ma, Juiming Lin, Jinran Lin, Wenyu Wu, Yiyi Gong, Jiucun Wang, Qingmei Liu
Int. J. Biol. Sci. 2023; 19(8): 2394-2408. doi:10.7150/ijbs.77649
Abstract Full text PDF PubMed PMC

Brain-derived extracellular vesicles promote bone-fat imbalance in Alzheimer's disease
Xixi Liu, Chunyuan Chen, Yaling Jiang, Meidan Wan, Bin Jiao, Xinxin Liao, Shanshan Rao, Chungu Hong, Qijie Yang, Yuan Zhu, Qianqian Liu, Zhongwei Luo, Ran Duan, Yiyi Wang, Yijuan Tan, Jia Cao, Zhengzhao Liu, Zhenxing Wang, Hui Xie, Lu Shen
Int. J. Biol. Sci. 2023; 19(8): 2409-2427. doi:10.7150/ijbs.79461
Abstract Full text PDF PubMed PMC

Decreased methylation of ZNF671 suppresses tumor progression by promoting MAPK6 transcription in laryngeal carcinoma
Wei Zhang, Ting Liu, Xinyi Li, Tianshu Li, Xiangchi Ma, Dongxu Zhao, Xudong Zhao
Int. J. Biol. Sci. 2023; 19(8): 2443-2457. doi:10.7150/ijbs.82692
Abstract Full text PDF PubMed PMC

YAP1 synergize with YY1 transcriptional co-repress DUSP1 to induce osimertinib resistant by activating the EGFR/MAPK pathway and abrogating autophagy in non-small cell lung cancer
Yue Ning, Hongmei Zheng, Yang Yang, Hongjing Zang, Weiyuan Wang, Yuting Zhan, Haihua Wang, Jiadi Luo, Qiuyuan Wen, Jinwu Peng, Juanjuan Xiang, Songqing Fan
Int. J. Biol. Sci. 2023; 19(8): 2458-2474. doi:10.7150/ijbs.79965
Abstract Full text PDF PubMed PMC

Over-activation of TRPM2 ion channel accelerates blood-spinal cord barrier destruction in diabetes combined with spinal cord injury rat
Susu Zhang, Jiaxin Zhao, Man Wu, Yongxiu Zhou, Xuejuan Wu, Anyu Du, Yibing Tao, Shanshan Huang, Shufang Cai, Mei Zhou, Tao Wei, Yanren Zhang, Ling Xie, Yanqing Wu, Jian Xiao
Int. J. Biol. Sci. 2023; 19(8): 2475-2494. doi:10.7150/ijbs.80672
Abstract Full text PDF PubMed PMC

Integrating Spatial Transcriptomics and Single-nucleus RNA Sequencing Reveals the Potential Therapeutic Strategies for Uterine Leiomyoma
Jianzhang Wang, Ping Xu, Gen Zou, Xuan Che, Xiaohong Jiang, Yuanmeng Liu, Xinqi Mao, Xinmei Zhang
Int. J. Biol. Sci. 2023; 19(8): 2515-2530. doi:10.7150/ijbs.83510
Abstract Full text PDF PubMed PMC

Anomanolide C suppresses tumor progression and metastasis by ubiquitinating GPX4-driven autophagy-dependent ferroptosis in triple negative breast cancer
Yan-Mei Chen, Wei Xu, Yang Liu, Jia-Hui Zhang, Yuan-Yuan Yang, Zhi-wen Wang, De-Juan Sun, Hua Li, Bo Liu, Li-Xia Chen
Int. J. Biol. Sci. 2023; 19(8): 2531-2550. doi:10.7150/ijbs.82120
Abstract Full text PDF PubMed PMC

Comprehensive Analyses Reveal Effects on Tumor Immune Infiltration and Immunotherapy Response of APOBEC Mutagenesis and Its Molecular Mechanisms in Esophageal Squamous Cell Carcinoma
Jie Yang, Tao Xiang, Shihao Zhu, Yueqiong Lao, Yuqian Wang, Tianyuan Liu, Kai Li, Yuling Ma, Ce Zhong, Shaosen Zhang, Wen Tan, Dongxin Lin, Chen Wu
Int. J. Biol. Sci. 2023; 19(8): 2551-2571. doi:10.7150/ijbs.83824
Abstract Full text PDF PubMed PMC

C-C motif chemokine receptor 2 inhibition reduces liver fibrosis by restoring the immune cell landscape
Yangkun Guo, Chong Zhao, Wenting Dai, Bowen Wang, Enjiang Lai, Yang Xiao, Chengwei Tang, Zhiyin Huang, Jinhang Gao
Int. J. Biol. Sci. 2023; 19(8): 2572-2587. doi:10.7150/ijbs.83530
Abstract Full text PDF PubMed PMC

LncRNA UCA1 Participates in De Novo Synthesis of Guanine Nucleotides in Bladder Cancer by Recruiting TWIST1 to Increase IMPDH1/2
Shan-Shan Liu, Jia-Shu Li, Mei Xue, Wen-Jing Wu, Xu Li, Wei Chen
Int. J. Biol. Sci. 2023; 19(8): 2599-2612. doi:10.7150/ijbs.82875
Abstract Full text PDF PubMed PMC

ACE2 negatively regulates the Warburg effect and suppresses hepatocellular carcinoma progression via reducing ROS-HIF1α activity
Fangyuan Dong, Hui Li, Limin Liu, Lin-Li Yao, Jiaofeng Wang, Danni Xiang, Jianxia Ma, Gansheng Zhang, Shan Zhang, Jun Li, Shu-Heng Jiang, Xiaona Hu, Jie Chen, Zhijun Bao
Int. J. Biol. Sci. 2023; 19(8): 2613-2629. doi:10.7150/ijbs.81498
Abstract Full text PDF PubMed PMC

Reviews

Methyltransferase Set7/9 as a Multifaceted Regulator of ROS Response
Alexandra Daks, Oleg Shuvalov, Olga Fedorova, Sergey Parfenyev, Hans-Uwe Simon, Nickolai A. Barlev
Int. J. Biol. Sci. 2023; 19(8): 2304-2318. doi:10.7150/ijbs.83158
Abstract Full text PDF PubMed PMC

A Lipid Perspective on Regulated Pyroptosis
Yun Qiu, Ya-Ning Shi, Neng Zhu, Shuo Zhang, Chan-Juan Zhang, Jia Gu, Peng He, Ai-Guo Dai, Li Qin
Int. J. Biol. Sci. 2023; 19(8): 2333-2348. doi:10.7150/ijbs.81017
Abstract Full text PDF PubMed PMC

B cells in tumor metastasis: friend or foe?
Yuqiu Xu, Yihao Mao, Yang Lv, Wentao Tang, Jianmin Xu
Int. J. Biol. Sci. 2023; 19(8): 2382-2393. doi:10.7150/ijbs.79482
Abstract Full text PDF PubMed PMC

Current Status in Rechallenge of Immunotherapy
Han Hu, Ke Wang, Rong Jia, Zi-Xun Zeng, Min Zhu, Yuan-Le Deng, Zhu-Juan Xiong, Jian-Ning Tang, Hua Xie, Yi Wang, Peng Zhang, Jin Zhou
Int. J. Biol. Sci. 2023; 19(8): 2428-2442. doi:10.7150/ijbs.82776
Abstract Full text PDF PubMed PMC

Dysregulated MicroRNAs in the Pathogenesis of Systemic Lupus Erythematosus: A Comprehensive Review
Daeun Choi, Jimin Kim, Jae Won Yang, Ji Hong Kim, Seoyeon Park, Jae Il Shin
Int. J. Biol. Sci. 2023; 19(8): 2495-2514. doi:10.7150/ijbs.74315
Abstract Full text PDF PubMed PMC

Influence of gut microbiota on resilience and its possible mechanisms
Jianhui Wang, Ting Zhou, Feng Liu, Yan Huang, Zhiyong Xiao, Yan Qian, Wenxia Zhou
Int. J. Biol. Sci. 2023; 19(8): 2588-2598. doi:10.7150/ijbs.82362
Abstract Full text PDF PubMed PMC

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