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Volume 14 (8); 2018

Editorial

Special issue on Computational Resources and Methods in Biological Sciences
Hao Lin, Shaoliang Peng, Jian Huang
Int. J. Biol. Sci. 2018; 14(8): 807-810. doi:10.7150/ijbs.27554
Abstract Full text PDF PubMed PMC

Research Papers

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Integrated multifactor analysis explores core dysfunctional modules in autism spectrum disorder
Yan Huang, Zhenghong Chang, Xiaodan Li, Shuang Liang, Ying Yi, Lijie Wu
Int. J. Biol. Sci. 2018; 14(8): 811-818. doi:10.7150/ijbs.24624
Abstract Full text PDF PubMed PMC


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Genome-wide Analyses on Single Disease Samples for Potential Biomarkers and Biological Features of Molecular Subtypes: A Case Study in Gastric Cancer
Wei Zeng, Nini Rao, Qian Li, Guangbin Wang, Dingyun Liu, Zhengwen Li, Yuntao Yang
Int. J. Biol. Sci. 2018; 14(8): 833-842. doi:10.7150/ijbs.24816
Abstract Full text PDF PubMed PMC


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GeneFuse: detection and visualization of target gene fusions from DNA sequencing data
Shifu Chen, Ming Liu, Tanxiao Huang, Wenting Liao, Mingyan Xu, Jia Gu
Int. J. Biol. Sci. 2018; 14(8): 843-848. doi:10.7150/ijbs.24626
Abstract Full text PDF PubMed PMC


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PRWHMDA: Human Microbe-Disease Association Prediction by Random Walk on the Heterogeneous Network with PSO
Chuanyan Wu, Rui Gao, Daoliang Zhang, Shiyun Han, Yusen Zhang
Int. J. Biol. Sci. 2018; 14(8): 849-857. doi:10.7150/ijbs.24539
Abstract Full text PDF PubMed PMC


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CRISPRMatch: An Automatic Calculation and Visualization Tool for High-throughput CRISPR Genome-editing Data Analysis
Qi You, Zhaohui Zhong, Qiurong Ren, Fakhrul Hassan, Yong Zhang, Tao Zhang
Int. J. Biol. Sci. 2018; 14(8): 858-862. doi:10.7150/ijbs.24581
Abstract Full text PDF PubMed PMC


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Identification of Inhibitors of MMPS Enzymes via a Novel Computational Approach
Jian Song, Jijun Tang, Fei Guo
Int. J. Biol. Sci. 2018; 14(8): 863-871. doi:10.7150/ijbs.24588
Abstract Full text PDF PubMed PMC


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Research on folding diversity in statistical learning methods for RNA secondary structure prediction
Yu Zhu, ZhaoYang Xie, YiZhou Li, Min Zhu, Yi-Ping Phoebe Chen
Int. J. Biol. Sci. 2018; 14(8): 872-882. doi:10.7150/ijbs.24595
Abstract Full text PDF PubMed PMC


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iRSpot-Pse6NC: Identifying recombination spots in Saccharomyces cerevisiae by incorporating hexamer composition into general PseKNC
Hui Yang, Wang-Ren Qiu, Guoqing Liu, Feng-Biao Guo, Wei Chen, Kuo-Chen Chou, Hao Lin
Int. J. Biol. Sci. 2018; 14(8): 883-891. doi:10.7150/ijbs.24616
Abstract Full text PDF PubMed PMC


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Identifying differentially expressed genes from cross-site integrated data based on relative expression orderings
Hao Cai, Xiangyu Li, Jing Li, Qirui Liang, Weicheng Zheng, Qingzhou Guan, Zheng Guo, Xianlong Wang
Int. J. Biol. Sci. 2018; 14(8): 892-900. doi:10.7150/ijbs.24548
Abstract Full text PDF PubMed PMC


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A Sequential Segment Based Alpha-Helical Transmembrane Protein Alignment Method
Han Wang, Jingru Wang, Li Zhang, Pingping Sun, Ning Du, Yanwen Li
Int. J. Biol. Sci. 2018; 14(8): 901-906. doi:10.7150/ijbs.24327
Abstract Full text PDF PubMed PMC


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MicroShare: Privacy-Preserved Medical Resource Sharing through MicroService Architecture
Yilong Yang, Quan Zu, Peng Liu, Defang Ouyang, Xiaoshan Li
Int. J. Biol. Sci. 2018; 14(8): 907-919. doi:10.7150/ijbs.24617
Abstract Full text PDF PubMed PMC


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Computational Design of Antiangiogenic Peptibody by Fusing Human IgG1 Fc Fragment and HRH Peptide: Structural Modeling, Energetic Analysis, and Dynamics Simulation of Its Binding Potency to VEGF Receptor
Lin Ning, Zhongyan Li, Zhengya Bai, Shasha Hou, Bifang He, Jian Huang, Peng Zhou
Int. J. Biol. Sci. 2018; 14(8): 930-937. doi:10.7150/ijbs.24582
Abstract Full text PDF PubMed PMC


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Classification of Sputum Sounds Using Artificial Neural Network and Wavelet Transform
Yan Shi, Guoliang Wang, Jinglong Niu, Qimin Zhang, Maolin Cai, Baoqing Sun, Dandan Wang, Mei Xue, Xiaohua Douglas Zhang
Int. J. Biol. Sci. 2018; 14(8): 938-945. doi:10.7150/ijbs.23855
Abstract Full text PDF PubMed PMC


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PTM-ssMP: A Web Server for Predicting Different Types of Post-translational Modification Sites Using Novel Site-specific Modification Profile
Yu Liu, Minghui Wang, Jianing Xi, Fenglin Luo, Ao Li
Int. J. Biol. Sci. 2018; 14(8): 946-956. doi:10.7150/ijbs.24121
Abstract Full text PDF PubMed PMC


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HBPred: a tool to identify growth hormone-binding proteins
Hua Tang, Ya-Wei Zhao, Ping Zou, Chun-Mei Zhang, Rong Chen, Po Huang, Hao Lin
Int. J. Biol. Sci. 2018; 14(8): 957-964. doi:10.7150/ijbs.24174
Abstract Full text PDF PubMed PMC


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RicyerDB: A Database For Collecting Rice Yield-related Genes with Biological Analysis
Jing Jiang, Fei Xing, Xiangxiang Zeng, Quan Zou
Int. J. Biol. Sci. 2018; 14(8): 965-970. doi:10.7150/ijbs.23328
Abstract Full text PDF PubMed PMC


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Predicting Potential Drugs for Breast Cancer based on miRNA and Tissue Specificity
Liang Yu, Jin Zhao, Lin Gao
Int. J. Biol. Sci. 2018; 14(8): 971-982. doi:10.7150/ijbs.23350
Abstract Full text PDF PubMed PMC


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Improving Prediction of Self-interacting Proteins Using Stacked Sparse Auto-Encoder with PSSM profiles
Yan-Bin Wang, Zhu-Hong You, Li-Ping Li, De-Shuang Huang, Feng-Feng Zhou, Shan Yang
Int. J. Biol. Sci. 2018; 14(8): 983-991. doi:10.7150/ijbs.23817
Abstract Full text PDF PubMed PMC

Reviews

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A comprehensive review of web-based resources of non-coding RNAs for plant science research
Peiran Liao, Shipeng Li, Xiuming Cui, Yun Zheng
Int. J. Biol. Sci. 2018; 14(8): 819-832. doi:10.7150/ijbs.24593
Abstract Full text PDF PubMed PMC


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Translational Bioinformatics for Cholangiocarcinoma: Opportunities and Challenges
Fuliang Qian, Junping Guo, Zhi Jiang, Bairong Shen
Int. J. Biol. Sci. 2018; 14(8): 920-929. doi:10.7150/ijbs.24622
Abstract Full text PDF PubMed PMC

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