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Volume 19 (1); 2023

Research Papers

Vimentin epigenetic deregulation in Bladder Cancer associates with acquisition of invasive and metastatic phenotype through epithelial-to-mesenchymal transition
Sara Monteiro-Reis, Vera Miranda-Gonçalves, Catarina Guimarães-Teixeira, Cláudia Martins-Lima, João Lobo, Diana Montezuma, Paula C. Dias, Helene Neyret-Kahn, Isabelle Bernard-Pierrot, Rui Henrique, Carmen Jerónimo
Int. J. Biol. Sci. 2023; 19(1): 1-12. doi:10.7150/ijbs.77181
Abstract Full text PDF PubMed PMC

RUNX2 stabilization by long non-coding RNAs contributes to hypertrophic changes in human chondrocytes
Dong Suk Yoon, Eun-Ji Kim, Sehee Cho, Soyeong Jung, Kyoung-Mi Lee, Kwang Hwan Park, Jin Woo Lee, Sung-Hwan Kim
Int. J. Biol. Sci. 2023; 19(1): 13-33. doi:10.7150/ijbs.74895
Abstract Full text PDF PubMed PMC

Histone Methyltransferase KMT2B Promotes Metastasis and Angiogenesis of Cervical Cancer by Upregulating EGF Expression
Dan Zhao, Hui Yuan, Yuan Fang, Jian Gao, Huimin Li, Mengge Li, Hui Cong, Chenglin Zhang, Yiyi Liang, Jin Li, Hancao Yang, Ming Yao, Min Du, Hong Tu, Yu Gan
Int. J. Biol. Sci. 2023; 19(1): 34-49. doi:10.7150/ijbs.72381
Abstract Full text PDF PubMed PMC

PROX1-mediated epigenetic silencing of SIRT3 contributes to proliferation and glucose metabolism in colorectal cancer
Lu Gan, Qingguo Li, Wei Nie, Yi Zhang, Hesheng Jiang, Cong Tan, Long Zhang, Jieyun Zhang, Qian Li, Pengcong Hou, Yitao Yuan, Xun Sun, Dongmei Liu, Weiqi Sheng, Tianshu Liu, Midie Xu, Weijian Guo
Int. J. Biol. Sci. 2023; 19(1): 50-65. doi:10.7150/ijbs.73530
Abstract Full text PDF PubMed PMC

miR-1275 targets MDK/AKT signaling to inhibit breast cancer chemoresistance by lessening the properties of cancer stem cells
Xu Han, Minghui Li, Jin Xu, Jingyue Fu, Xinyang Wang, Jingyi Wang, Tiansong Xia, Shui Wang, Ge Ma
Int. J. Biol. Sci. 2023; 19(1): 89-103. doi:10.7150/ijbs.74227
Abstract Full text PDF PubMed PMC

Inhibition of androgen receptor enhanced the anticancer effects of everolimus through targeting glucose transporter 12
Bo Cao, Ruiyang Zhao, Hanghang Li, Xingming Xu, Jingwang Gao, Lin Chen, Bo Wei
Int. J. Biol. Sci. 2023; 19(1): 104-119. doi:10.7150/ijbs.75106
Abstract Full text PDF PubMed PMC

The developmental regulator HAND1 inhibits gastric carcinogenesis through enhancing ER stress apoptosis via targeting CHOP and BAK which is augmented by cisplatin
Yeye Kuang, Zhanglian He, Lili Li, Chan Wang, Xiaoqing Cheng, Qinglan Shi, Guoxiang Fu, Jianming Ying, Qian Tao, Xiaotong Hu
Int. J. Biol. Sci. 2023; 19(1): 120-136. doi:10.7150/ijbs.76345
Abstract Full text PDF PubMed PMC

N-glycosylation-mediated CD147 accumulation induces cardiac fibrosis in the diabetic heart through ALK5 activation
Mingchuan Liu, Tingwei Peng, Lang Hu, Min Wang, Dong Guo, Bingchao Qi, Gaotong Ren, Di Wang, Yunqing Li, Liqiang Song, Jianqiang Hu, Yan Li
Int. J. Biol. Sci. 2023; 19(1): 137-155. doi:10.7150/ijbs.77469
Abstract Full text PDF PubMed PMC

A stapled chromogranin A-derived peptide homes in on tumors that express αvβ6 or αvβ8 integrins
Matteo Monieri, Paolo Rainone, Angelina Sacchi, Alessandro Gori, Anna Maria Gasparri, Angela Coliva, Antonio Citro, Benedetta Ferrara, Martina Policardi, Silvia Valtorta, Arianna Pocaterra, Massimo Alfano, Dean Sheppard, Lorenzo Piemonti, Rosa Maria Moresco, Angelo Corti, Flavio Curnis
Int. J. Biol. Sci. 2023; 19(1): 156-166. doi:10.7150/ijbs.76148
Abstract Full text PDF PubMed PMC

Tendon Cells Root Into (Instead of Attach to) Humeral Bone Head via Fibrocartilage-Enthesis
Zheng Wang, Chi Ma, Diane Chen, Caitlin Haslett, Chunmei Xu, Changchun Dong, Xiaofang Wang, Minghao Zheng, Yan Jing, Jian Q. Feng
Int. J. Biol. Sci. 2023; 19(1): 183-203. doi:10.7150/ijbs.79007
Abstract Full text PDF PubMed PMC

TGFβ Governs the Pleiotropic Activity of NDRG1 in Triple-Negative Breast Cancer Progression
Araceli López-Tejada, Carmen Griñán-Lisón, Adrián González-González, Francisca E. Cara, Rafael J. Luque, Carmen Rosa-Garrido, José L. Blaya-Cánovas, Alba Navarro-Ocón, María Valenzuela-Torres, Marisa Parra-López, Jesús Calahorra, Isabel Blancas, Juan A. Marchal, Sergio Granados-Principal
Int. J. Biol. Sci. 2023; 19(1): 204-224. doi:10.7150/ijbs.78738
Abstract Full text PDF PubMed PMC

HIF-1α/YAP Signaling Rewrites Glucose/Iodine Metabolism Program to Promote Papillary Thyroid Cancer Progression
Hongjun Song, Zhongling Qiu, Yang Wang, Chuang Xi, Guoqiang Zhang, Zhenkui Sun, Quanyong Luo, Chentian Shen
Int. J. Biol. Sci. 2023; 19(1): 225-241. doi:10.7150/ijbs.75459
Abstract Full text PDF PubMed PMC

TREM-1 governs NLRP3 inflammasome activation of macrophages by firing up glycolysis in acute lung injury
Wen-Jing Zhong, Tian Liu, Hui-Hui Yang, Jia-Xi Duan, Jin-Tong Yang, Xin-Xin Guan, Jian-Bing Xiong, Yan-Feng Zhang, Chen-Yu Zhang, Yong Zhou, Cha-Xiang Guan
Int. J. Biol. Sci. 2023; 19(1): 242-257. doi:10.7150/ijbs.77304
Abstract Full text PDF PubMed PMC

Validation of ESM1 Related to Ovarian Cancer and the Biological Function and Prognostic Significance
Yu-kun Li, Tian Zeng, Yang Guan, Jue Liu, Nian-chun Liao, Meng-jie Wang, Ke-xin Chen, Xian-yu Luo, Chang-ye Chen, Fei-fei Quan, Juan Wang, Qun-feng Zhang, Juan Zou
Int. J. Biol. Sci. 2023; 19(1): 258-280. doi:10.7150/ijbs.66839
Abstract Full text PDF PubMed PMC

Nesfatin-1 Stimulates CCL2-dependent Monocyte Migration And M1 Macrophage Polarization: Implications For Rheumatoid Arthritis Therapy
Jun-Way Chang, Shan-Chi Liu, Yen-You Lin, Xiu-Yuan He, Yi-Syuan Wu, Chen-Ming Su, Chun-Hao Tsai, Hsien-Te Chen, Yi-Ching Fong, Sung-Lin Hu, Chien-Chung Huang, Chih-Hsin Tang
Int. J. Biol. Sci. 2023; 19(1): 281-293. doi:10.7150/ijbs.77987
Abstract Full text PDF PubMed PMC

Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury
Juan Zhang, Zhi-Lin Luan, Xiao-Kui Huo, Min Zhang, Christophe Morisseau, Cheng-Peng Sun, Bruce D. Hammock, Xiao-Chi Ma
Int. J. Biol. Sci. 2023; 19(1): 294-310. doi:10.7150/ijbs.78097
Abstract Full text PDF PubMed PMC

BST2 induced macrophage M2 polarization to promote the progression of colorectal cancer
Xuefeng He, Huaijun Chen, Xinyang Zhong, Yaxian Wang, Zijuan Hu, Huixia Huang, Senlin Zhao, Ping Wei, Debing Shi, Dawei Li
Int. J. Biol. Sci. 2023; 19(1): 331-345. doi:10.7150/ijbs.72538
Abstract Full text PDF PubMed PMC

Neutrophil Extracellular Traps Delay Diabetic Wound Healing by Inducing Endothelial-to-Mesenchymal Transition via the Hippo pathway
Shuofei Yang, ShuangShuang Wang, Liang Chen, Zheyu Wang, Jiaquan Chen, Qihong Ni, Xiangjiang Guo, Lan Zhang, Guanhua Xue
Int. J. Biol. Sci. 2023; 19(1): 347-361. doi:10.7150/ijbs.78046
Abstract Full text PDF PubMed PMC

Reviews

Targeting FGF21 in cardiovascular and metabolic diseases: from mechanism to medicine
Huiling Tan, Tong Yue, Zhengfang Chen, Weiming Wu, Suowen Xu, Jianping Weng
Int. J. Biol. Sci. 2023; 19(1): 66-88. doi:10.7150/ijbs.73936
Abstract Full text PDF PubMed PMC

Exosomes in Genitourinary Cancers: Emerging Mediators of Drug Resistance and Promising Biomarkers
Zeyi Lu, yuanlei Chen, Wenqin Luo, Lifeng Ding, Huan Wang, Yang Li, Bo wen Yang, Liangliang Ren, Qiming Zheng, Haiyun Xie, Ruyue Wang, Chenhao Yu, Yudong Lin, Zhenwei Zhou, Liqun Xia, Gonghui Li
Int. J. Biol. Sci. 2023; 19(1): 167-182. doi:10.7150/ijbs.78321
Abstract Full text PDF PubMed PMC

Insights into the roles and pathomechanisms of ceramide and sphigosine-1-phosphate in nonalcoholic fatty liver disease
Cheng Zhu, Qian Huai, Xu Zhang, Hanren Dai, Xiaolei Li, Hua Wang
Int. J. Biol. Sci. 2023; 19(1): 311-330. doi:10.7150/ijbs.78525
Abstract Full text PDF PubMed PMC

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