Volume 22, Issue 1

open access Global reach, higher impact

Volume 22 (1); 2026

Research Papers

LAPTM4B Confers Resistance to EGFR-TKIs by Suppressing the Proteasomal Degradation of ATP1A1 in Non-small Cell Lung Cancer
Dan Liu, Minxia Liu, Dongjin Lv, Yuxiang Li, Hongjuan Guo, Bingxiao Lu, Hao Leng, Ruyu Yan, Hongtao Yu, Tomas Blom, Kecheng Zhou
Int. J. Biol. Sci. 2026; 22(1): 1-24. doi:10.7150/ijbs.115365
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Alleviation of mutant TDP-43-mediated neuropathology by inducible stem cells in monkeys
Xichen Song, Caijuan Li, Yang Yang, Chunhui Huang, Min Chen, Song Lin, Zhonghai Huang, Wei Wang, Kai Liao, Huiyi Wei, Lu Wang, Hao Xu, Yizhi Chen, Yingqi Lin, Jiawei Li, Zhen Dai, Wenguang Xie, Xiao Zheng, Jianhao Wu, Jiale Gao, Jiaxi Wu, Zhuchi Tu, Libing Zhou, Lu Huang, Chaoran Ren, Kwok-Fai So, Peng Yin, Huiming Yang, Shihua Li, Liangxue Lai, Xiao-Jiang Li, Sen Yan
Int. J. Biol. Sci. 2026; 22(1): 25-42. doi:10.7150/ijbs.122557
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Dual-pathway mechanism of vanadium-induced hepatotoxicity in ducks: Synergistic crosstalk between glucose homeostasis disruption and NADH/FSP1/COQ10 axis-driven ferroptosis
Huawei Chen, Xueyan Dai, Zhiwei Xiong, Huabin Cao, Chenghong Xing, Haotang Li, Xiaona Gao, Mingwen Hu, Fan Yang
Int. J. Biol. Sci. 2026; 22(1): 43-59. doi:10.7150/ijbs.123482
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The IL-33/ST2 Axis Promotes Traumatic Heterotopic Ossification by Driving Macrophage and Mast Cell-Mediated Inflammation via Autophagy Defects
Zhenyu Chen, Yi Xu, Cheng Qu, Gang Luo, Zhuochang Cai, Hang Liu, Ziyang Sun, Chao Zhou, Juehong Li, Cunyi Fan
Int. J. Biol. Sci. 2026; 22(1): 60-85. doi:10.7150/ijbs.122706
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A SENP7-SIRT1-IL-10 Axis Driven by DeSUMOylation Promotes Breg Differentiation and Immune Evasion in Colorectal Cancer
Yuhan Liao, Xinghua Zhuo, Yuan Huang, Huimeng Xu, Zhe Hao, Lanhui Huang, Haoxuan Zheng, Jun Zhou
Int. J. Biol. Sci. 2026; 22(1): 111-125. doi:10.7150/ijbs.118896
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Hepatic Stellate Cell-derived IL-11 Exacerbates Liver Fibrosis via Interplay between HSCs and Macrophages
Yu Zhang, Fangfang He, Mozi Lei, Wenhui Fan, Xingyu Liu, Ying Tao, Weinan Wang, Bingshun Wang, Likun Gong, Jing Chen
Int. J. Biol. Sci. 2026; 22(1): 126-141. doi:10.7150/ijbs.119659
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H3K27 Acetylation-driven IGF2BP2 Mutates during the Aging of MSCs, thereby Influencing Osteogenic Differentiation and Bone Aging
Zimo Zhou, Kai Kang, Heran Wang, Boya Wen, Da Liu
Int. J. Biol. Sci. 2026; 22(1): 142-160. doi:10.7150/ijbs.122708
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Procyanidin Suppresses Tumor Growth by Activating the B-Cell MAPK Pathway through Remodulation of the Gut Microbiota and Metabolites in Hepatocellular Carcinoma
Ran Huo, Chen-Zheng Gu, Yang Liu, Zi-Xian Wei, Te Liu, Jie Zhu, Lin Ding, Yu Liu, Chu-Yu Wang, Yi-Ni Li, Xin-Yi He, Wen-Jing Yang, Bei-Li Wang, Yun-Wei Wei, Wei Guo
Int. J. Biol. Sci. 2026; 22(1): 161-177. doi:10.7150/ijbs.113217
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SIRT6-Mediated Regulation of TFAM: A Central Mechanism Connecting Nuclear and Mitochondrial Transcriptional Processes and Mitophagy
Meimei Jiang, Jiehan Li, Ning Ding, Guiyun Jia, Siming Wu, Nannan Liu, Ying Kang, Ge Zhang, Jiawei Wu, Lingling Zhang, Yingjie Zhang
Int. J. Biol. Sci. 2026; 22(1): 178-200. doi:10.7150/ijbs.120007
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Review

Therapy-induced mRNA, rRNA and tRNA methylation alterations confer tolerance phenotype in tumor cells: mechanism and implications
Anfeng Jiang, Shujie Liu, Zhiyuan Li, Xiongzhou Zhang, Minghao Duan, Bin Li
Int. J. Biol. Sci. 2026; 22(1): 86-110. doi:10.7150/ijbs.120764
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