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Volume 21 (10); 2025

Research Papers

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Inhibition of Mettl3 alleviates low-dose cisplatin-induced renal fibrosis and enhances the chemotherapeutic efficacy in mouse models of cancer
Yuxin Xie, Huiling Li, Jian Pan, Yijian Li, Dongshan Zhang
Int. J. Biol. Sci. 2025; 21(10): 4293-4311. doi:10.7150/ijbs.117443
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Stabilization of OLFML1 via m6A Reader IGF2BP3 Drives CSC Characteristics Through Hedgehog Pathway Activation in CRC
Yan Zhong, Jingfeng Liu, Wenwen Lin, Tian Peng, Lingfang Gao, Lan Shen, Ping Wang, Zhiyan Hu, Ting Long, Zuguo Li, Jingquan Liu
Int. J. Biol. Sci. 2025; 21(10): 4334-4352. doi:10.7150/ijbs.111032
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Undercarboxylated OCN Inhibits Chondrocyte Hypertrophy and Osteoarthritis Development through GPRC6A/HIF-1α Cascade
Zhangzhen Du, Yongqi Zhao, Ke Zhang, Qiaozhen Qin, Changyi Luo, Jiamei Wu, Heyang Zhang, Shuirong Liu, Zhenhua Xu, Jing Zheng, Shuli Fan, Xiaoxia Jiang, Xu Li, Yan Wang
Int. J. Biol. Sci. 2025; 21(10): 4353-4373. doi:10.7150/ijbs.105560
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FABP7-mediated lipid-laden macrophages drive the formation of pre-metastatic niche and liver metastasis
Shaowan Xu, Xin Peng, Zhenfang Wang, Chenchen Le, Xiangkun Wu, Zhicheng Zeng, Sisi Zeng, Ceng Zhang, Mingxing Qiu, Xin Zou, Hongxia Zhang, Feifei Wang, Wei Kang, Yanqing Ding, Li Liang
Int. J. Biol. Sci. 2025; 21(10): 4388-4409. doi:10.7150/ijbs.110750
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Reviews

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Beyond polarization: macrophage senescence in immunoregulation and cancer therapy
Mei Song, Lifen Zhang, Xiaofeng Dai, Shiliang Ji, Jiayin Shen, Weiling He
Int. J. Biol. Sci. 2025; 21(10): 4312-4333. doi:10.7150/ijbs.115921
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Tryptophan metabolism as a target in gut microbiota, ageing and kidney disease
Hua Miao, Shui-Juan Zhang, Xin Wu, Ping Li, Ying-Yong Zhao
Int. J. Biol. Sci. 2025; 21(10): 4374-4387. doi:10.7150/ijbs.115359
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